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Prevalence of hematinics deficiency amongst female students and its correction

Indian Journal of Hematology and Blood Transfusion volume 23, pages 88–91 (2007)Cite this article

Abstract

Background

Nutritional anemia (NA) is common in India. While iron deficiency (ID) is a well recognized cause of NA, prevalence of deficiencies of other hematinics is not systematically investigated.

Setting

Seventy students of a junior class of a polytechnic and 202 inmates of girl students home were taken up for study.

Methods

Students were given a questionnaire to elicit anemia related symptoms. Blood was collected for complete blood count (CBC), serum ferritin, folic acid and vitamin B12. Students of polytechnic received hematinic at bed time during their menstrual periods whereas inmates of students home received hematinic at bed time, 3 days in a week. After 6 months blood tests were repeated in those who completed the treatment. CBC was done on Coulter counter and ferritin, folic acid and vitamin B12 were assayed by chemiluminescence. Students were divided into three groups-(1) Control group with Hb 12.0 g/dl or more and ferritin 15.0 ng/ml or more; (2) ID Group with Hb 12.0 g/dl or more and ferritin less than 15.0 ng/ml; and (3) Iron Deficiency Anemia (IDA) group with Hb less tha 12.0 g/dl and ferritin less than 15.0 ng/ml.

Statistics

Basal parameters of three groups were compared using students t test. Change in parameters with treatment was compared using paired students t test.

Results

Median age-16 years (range 10–25). Anemia ( Hb < 12.0 g/dl)-94 (34.6%); MCV < 80 fl-153 (56.3%); MCH < 27 pg-167 (61.4%); Ferritin < 15.0 ng/ml-161 (59.2%); Folic acid < 3.5 ng/ml-34 (12.5%); Vitamin B12 < 258 pg/ml-133 (48.9%) Pre-therapy: (1) Hb, MCV, MCH and ferritin significantly lower in ID and IDA Groups compared to control group. (2) Hb, MCV, MCH and Ferritin significantly lower in IDA Group as compared to ID Group.

Post-therapy

(1) IDA group showed significant increase in Hb, MCV, MCH, ferritin, folic acid and vitamin B12. (2) final Hb (11.26+1.07) and ferritin (7.46+4.81) in IDA Group were subnormal. (3) MCV, MCH, ferritin, folic acid and vitamin B12 increased significantly in ID Group and control group.

Conclusions

(1) Nutritional anemia is common amongst asymptomatic young female students. (2) Deficiencies of iron, folic acid and vitamin B12 are common and coexist. (3) 105 mg elemental iron for 3 days in a week for 6 months is not adequate to correct IDA. (4) 105 mg iron for 3 days in a week is enough to correct ID. (5) Non-anemic individuals with ID have iron deficient erythropoiesis. (6) Non-anemic individuals without ID, in this cohort, also had iron deficient eryhtropoiesis.

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References

  1. Mehta BC, Patel JC (1969) Anemia in a population with low socio-economic status. Indian J Med Sci 23:349–357

    PubMed  Google Scholar 

  2. Gopalan C (1999) Women and nutrition in India. J Nutrit Dietet 36:95–107

    Google Scholar 

  3. Roy S, Ray S (2000) Prevention of malnutrition. J Indian Med Assn 98:510–11

    CAS  Google Scholar 

  4. Spence D (2001) Uses of error: Knowledge gaps. Lancet 358:1934

    PubMed  Article  CAS  Google Scholar 

  5. Mehta BC, Pathare SM, D’Costa H, Patel JC (1970) Serum folate and B12 levels in iron deficiency anemia. Indian J Med Sci 24:781–785

    Google Scholar 

  6. Ashavaid TF, Todur SP, Dherai AJ (2004) Health status of Indian population-current scenario. J Assn Phys India 52:363–369

    Google Scholar 

  7. Das KVK (1980) Nutritional anemias in India. J Assn Phys India 28:521–523

    Google Scholar 

  8. Cowan B, Bharucha C (1073) Iron deficiency in tropics. Clinics Hematol 2:353–362

    Google Scholar 

  9. Nelson R, Chawala M, Conolly P, Laporte J (1978) Ferritin as index of bone marrow iron stores. Southern Med J 71:1482–1484

    CAS  Google Scholar 

  10. Hallberg A, Bengtsson C, Lapidus L, Lindstedt G, Lundberg PA, Hulten L (1993) Screening for iron deficiency: an analysis based on bone marrow examination and serum ferritin determination in a population sample of women. Brit J Hematol 85:787–798

    Article  CAS  Google Scholar 

  11. Holyoake TL, Stott DJ, McKay PJ, Hendry A, MacDonald JB, Lucie NP (1993) Use of plasma ferritin concentration to diagnose iron deficiency in elderly patients. J Clin Pathol 46:857–860

    PubMed  Article  CAS  Google Scholar 

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Affiliations

  1. Laboratory Medicine, Blood Bank & Dr JC Patel Medical Research Department, Head Smt Santokben Chhotalal Mehta Hematology Department, BSES MG Hospital, SV Road, Andheri (West), Mumbai, 400 058, India

    B. C. Mehta, R. M. Kabeer & Y. Patel

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  1. B. C. Mehta
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  2. R. M. Kabeer
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  3. Y. Patel
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Mehta, B.C., Kabeer, R.M. & Patel, Y. Prevalence of hematinics deficiency amongst female students and its correction. Indian J Hematol Blood Transfus 23, 88–91 (2007). https://doi.org/10.1007/s12288-008-0014-y

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  • DOI: https://doi.org/10.1007/s12288-008-0014-y

Keywords

  • Nutritional anemia
  • Iron deficiency
  • Iron deficiency anemia
  • B12 deficiency
  • Folic acid deficiency
  • Iron deficient erythropoiesis
  • Dose of elemental iron