Skip to main content

Advertisement

Log in

Pure ground glass opacity (GGO) on chest CT: a rare presentation of lung metastasis of Malignant Phyllodes Tumor

  • Case Report
  • Published:
Breast Cancer Aims and scope Submit manuscript

Abstract

Lung is the most common target organ for distant metastasis of phyllodes tumor (PT), where the metastatic tumors are mostly seen as nodules or masses. We report here a rare case in which pure ground-glass opacity (GGO) was observed on chest CT about 3 years after the initial treatment of breast PT. After the lung lobectomy, we histologically confirmed that it should be diagnosed as a metastasis of PT. GGO rarely shows on metastatic tumors, and no reports have been made on GGO thus far in connection with metastasis of PT. Thus, in case GGO was found on the CT of patients having a history of PT, we suggest to take possible distant-metastasis into consideration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Kapris I, Nasiri N, A’Hern R, Healy V, Gui GPH. Outcome and predictive factors of local recurrence and distant metastasis following primary surgical treatment of high-grade malignant phyllodes tumors of the breast. Eur J Surg Oncol. 2001;27:723–30.

    Article  Google Scholar 

  2. Guerrero MA, Ballard BR, Grau AM. Malignant phyllodes tumor of the breast: review of the literature and case report of stromal growth. Surg Oncol. 2003;12:27–37.

    Article  Google Scholar 

  3. Hawkins RE, Schofield JB, Wiltshaw E, Fisher C, McKinna JA. Ifosphamide is an active drug for chemotherapy of metastatic cystosarcoma phyllodes. Cancer. 1992;69:2271–5.

    Article  CAS  Google Scholar 

  4. Kessinger A, Foley JF, Lemon HM, Miller DM. Metastic cystosarcoma phyllodes: a case report and review of the literature. J Surg Oncol. 1972;4:131–47.

    Article  CAS  Google Scholar 

  5. Yagishita M, Nambu Y, Ishigaki M, Okada T, Yamanouchi K, Toga H, et al. Pulmonary metastatic malignant phyllodes tumor showing multiple thin walled cavities. Nihon Kokyuki Gakkai Zasshi. 1999;37:61–6.

    CAS  PubMed  Google Scholar 

  6. Austin JH, Müller NL, Friedman PJ, Hansell DM, Naidich DP, Remy-Jardin M, et al. Glossary of terms for CT of the lungs: recommendations of the Nomenclature Committee of the Fleischner Society. Radiology. 1996;200:327–31.

    Article  CAS  Google Scholar 

  7. Jannet C, Eric JS. Ground-glass opacity at CT: the ABCs. AJR. 1997;169:355–67.

    Article  Google Scholar 

  8. Seo FB, Im FG, Goo FM, Chung MF, Kim MY. Atypical pulmonary metastasis: spectrum of radiologic findings. Radio Gr. 2001;21:403–7.

    CAS  Google Scholar 

  9. Okita R, Yamashita M, Nakata M, Teramoto N, Bessho A, Mogami H. Multiple ground-glass opacity in metastasis of malignant melanoma diagnosed by lung biopsy. Ann Thorac Surg. 2005;79:e1–2.

    Article  Google Scholar 

  10. Kim SB, Lee S, Koh MJ, Lee IS, Moon CH, Jung SM, et al. Ground-glass opacity in lung metastasis from breast cancer: a case report. Tubercul Respir Dis. 2013;74:32–6.

    Article  Google Scholar 

  11. Hawkins RE, Schofield JB, Fisher C, Wiltshaw E, McKinna JA. The clinical and histologic criteria that predict metastases from cystosarcoma phyllodes. Cancer. 1992;69:141–7.

    Article  CAS  Google Scholar 

  12. Silver SA, Tavassoli FA. Osteosarcomatous differentiation in phyllodes tumors. Am J Surg Pathol. 1999;23:815–21.

    Article  CAS  Google Scholar 

  13. Morcos BB, Baker B, Hashem SA. Ileocaecal intussusception secondary to metastatic phyllodes tumour of the breast. Ann R Coll Surg Engl. 2010;92:29–30.

    Article  Google Scholar 

  14. Chang SS, Nakano T, Okamoto T, Takabatake D. Pulmonary metastasis from a phyllodes tumor of the breast developing sixteen years after initial surgery. Kyobu Geka. 2015;68:1000–3.

    PubMed  Google Scholar 

  15. Ganti S, Svennevik E, Ali FSM, Anikin V. Successful resection of giant solitary pulmonary metastasis from a phyllodes tumor. Ann Thorac Surg. 2007;84:1750–2.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shoko Nakamura.

Ethics declarations

Conflict of interest

The authors have no conflicts to disclose.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nakamura, S., Goto, T., Nara, S. et al. Pure ground glass opacity (GGO) on chest CT: a rare presentation of lung metastasis of Malignant Phyllodes Tumor. Breast Cancer 27, 1187–1190 (2020). https://doi.org/10.1007/s12282-020-01122-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12282-020-01122-y

Keywords

Navigation