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A meta-analysis of the benefits of mindfulness-based stress reduction (MBSR) on psychological function among breast cancer (BC) survivors



Psychological issue is the most common co-morbidity of women with breast cancer (BC) after receiving treatment. Effective coping with this problem is significant importance. The aim of this meta-analysis is to evaluate the benefits of mindfulness-based stress reduction (MBSR) on psychological distress among breast cancer survivors.


PUBMED, EMBASE, and the Cochrane Central Register of Controlled Trials were systematically searched from their inception to June 30, 2014. Two reviewers independently reviewed and extracted the data. The primary outcomes of interest were psychological domains. Review Manager 5.3 was used to pool collected data.


Nine articles involving 964 participants were identified. Compared with those in control group, patients in MBSR group have a significant improvement on psychological domains: depression [mean difference (MD), 5.09; 95 % confidence interval (CI), 3.63–6.55; P < 0.00001], anxiety (MD, 2.79; 95 % CI, 1.62–3.96; P < 0.00001), stress (MD, 4.10; 95 % CI, 2.46–5.74; P < 0.00001). MBSR can also improve the overall quality of life (QOL) (MD, −1.16; 95 % CI, −2.21 to −0.12; P = 0.03).


On the basis of our findings, MBSR shows a positive effect on psychological function and QOL of breast cancer survivors. This approach can be recommended to breast cancer patients as a part of their rehabilitation.

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All authors wish to thank the professor Zhou, JR for her kind suggestions. No potential conflicts of interest were disclosed.

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Correspondence to Hua-ping Huang.

Additional information

A protocol was registered on PROSPERO (the international register of systematic reviews; registration number: CRD42014009409).

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Huang, Hp., He, M., Wang, Hy. et al. A meta-analysis of the benefits of mindfulness-based stress reduction (MBSR) on psychological function among breast cancer (BC) survivors. Breast Cancer 23, 568–576 (2016).

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  • Breast cancer
  • Mindfulness-based stress reduction
  • Psychological
  • Quality of life
  • Meta-analysis