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Two cases of diabetic mastopathy: MR imaging and pathological correlation

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Abstract

Diabetic mastopathy is a rare benign condition associated with long-standing diabetes mellitus and presents with breast lumps. This report describes two cases in which diffusion-weighted images (DWI) on magnetic resonance imaging were quite different from each other. In case 1, there were hyperintense lesions on DWI, and surgically removed specimens revealed ductitis with marked lymphocytic infiltration. In case 2, no abnormal intensity was depicted on DWI, and biopsy specimens showed dense stromal fibrosis with mild perivascular lymphocytic infiltration that corresponded to previous reports. Although it is reported that diabetic mastopathy is composed of dense fibrous tissue with low cellularity that results in no hyperintense lesion on DWI, in cases with marked lymphocytic infiltration, strong hyperintensity can be seen on DWI mimicking malignant breast tumors.

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Authors and Affiliations

  1. Department of Radiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu City, Shizuoka Prefecture, 431-3192, Japan

    Hatsuko Nasu, Akiko Ikeda & Harumi Sakahara

  2. Department of Breast Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan

    Hiroyuki Ogura, Chikako Teruya & Kei Koizumi

  3. Department of Pathology, Hamamatsu University Hospital, Hamamatsu, Japan

    Mana Kinoshita, Takashi Tsuchida & Satoshi Baba

  4. Department of Health Science, Pathology and Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Japan

    Katsutoshi Miura

  5. Department of Radiology, Hamamatsu University Hospital, Hamamatsu, Japan

    Yasuo Takehara

Authors
  1. Hatsuko Nasu
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  2. Akiko Ikeda
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  3. Hiroyuki Ogura
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  4. Chikako Teruya
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  5. Kei Koizumi
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  6. Mana Kinoshita
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  7. Takashi Tsuchida
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  8. Satoshi Baba
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  9. Katsutoshi Miura
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  10. Yasuo Takehara
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  11. Harumi Sakahara
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Corresponding author

Correspondence to Hatsuko Nasu.

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Nasu, H., Ikeda, A., Ogura, H. et al. Two cases of diabetic mastopathy: MR imaging and pathological correlation. Breast Cancer 22, 552–556 (2015). https://doi.org/10.1007/s12282-012-0407-5

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  • DOI: https://doi.org/10.1007/s12282-012-0407-5

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