References
Pappas PG, Kauffman CA, Andes D, et al.: Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009, 48:503–535.
Ernst ME, Klepser ME, Wolfe EJ, Pfaller MA: Antifungal dynamics of LY 303366, an investigational echinocandin B analog, against Candida ssp. Diagn Microbiol Infect Dis 1996, 26:125–131.
Andes DR, Diekema DJ, Pfaller MA, et al.: In vivo pharmacodynamic target investigation for micafungin against Candida albicans and C. glabrata in a neutropenic murine candidiasis model. Antimicrob Agents Chemother 2008, 52:3497–3503.
Stevens DA, Espiritu M, Parmar R: Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations. Antimicrob Agents Chemother 2004, 48:3407–3411.
Arathoon EG, Gotuzzo E, Noriega LM, et al.: Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases. Antimicrob Agents Chemother 2002, 46:451–457.
Villanueva A, Arathoon EG, Gotuzzo E, et al.: A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis. Clin Infect Dis 2001, 33:1529–1535.
Disclosure
No potential conflict of interest relevant to this article was reported.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Klepser, M.E. Safety and Efficacy Data for High-Dose Caspofungin. Curr Fungal Infect Rep 4, 59–61 (2010). https://doi.org/10.1007/s12281-010-0017-7
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12281-010-0017-7