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Safety and Efficacy Data for High-Dose Caspofungin

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References

  1. Pappas PG, Kauffman CA, Andes D, et al.: Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009, 48:503–535.

    Article  PubMed  CAS  Google Scholar 

  2. Ernst ME, Klepser ME, Wolfe EJ, Pfaller MA: Antifungal dynamics of LY 303366, an investigational echinocandin B analog, against Candida ssp. Diagn Microbiol Infect Dis 1996, 26:125–131.

    Article  PubMed  CAS  Google Scholar 

  3. Andes DR, Diekema DJ, Pfaller MA, et al.: In vivo pharmacodynamic target investigation for micafungin against Candida albicans and C. glabrata in a neutropenic murine candidiasis model. Antimicrob Agents Chemother 2008, 52:3497–3503.

    Article  PubMed  CAS  Google Scholar 

  4. Stevens DA, Espiritu M, Parmar R: Paradoxical effect of caspofungin: reduced activity against Candida albicans at high drug concentrations. Antimicrob Agents Chemother 2004, 48:3407–3411.

    Article  PubMed  CAS  Google Scholar 

  5. Arathoon EG, Gotuzzo E, Noriega LM, et al.: Randomized, double-blind, multicenter study of caspofungin versus amphotericin B for treatment of oropharyngeal and esophageal candidiases. Antimicrob Agents Chemother 2002, 46:451–457.

    Article  PubMed  CAS  Google Scholar 

  6. Villanueva A, Arathoon EG, Gotuzzo E, et al.: A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis. Clin Infect Dis 2001, 33:1529–1535.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Michael E. Klepser.

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Klepser, M.E. Safety and Efficacy Data for High-Dose Caspofungin. Curr Fungal Infect Rep 4, 59–61 (2010). https://doi.org/10.1007/s12281-010-0017-7

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