Nano Research

, Volume 9, Issue 10, pp 2889–2903 | Cite as

An anisotropic propagation technique for synthesizing hyperbranched polyvillic gold nanoparticles

  • Aaron S. Schwartz-Duval
  • Santosh K. Misra
  • Prabuddha Mukherjee
  • Elyse Johnson
  • Alvin S. Acerbo
  • Dipanjan PanEmail author
Research Article


Of late, many synthesis processes have been studied to develop irregular nano-morphologies of gold nanostructures for biomedical applications in order to increase the efficacy of nanoparticle theranostics, tune the plasmonic absorbance spectra, and increase the sensitivity of biomolecule detection through surface enhanced Raman spectroscopy. Here we report, a novel, non-seed mediated versatile single pot synthesis method capable of producing hyperbranched gold “nano-polyvilli” with more than 50–90 branching nanowires propagating from a single origin within each structure. The technique was capable of achieving precise tuning of the branch propagation where the branching could be controlled by varying the duration of incubation, temperature, and hydrogen ion concentration.


gold nanoparticles surface enhanced Raman spectroscopy (SERS) anisotropy asymmetric nanocrystallization 


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An anisotropic propagation technique for synthesizing hyperbranched polyvillic gold nanoparticles
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Supplementary material, approximately 2.75 MB.


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Copyright information

© Tsinghua University Press and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Aaron S. Schwartz-Duval
    • 1
    • 2
  • Santosh K. Misra
    • 1
    • 2
  • Prabuddha Mukherjee
    • 1
  • Elyse Johnson
    • 3
  • Alvin S. Acerbo
    • 4
  • Dipanjan Pan
    • 1
    • 2
    Email author
  1. 1.Department of Bioengineering and Beckman InstituteUniversity of Illinois, Urbana-ChampaignUrbanaUSA
  2. 2.Biomedical Research CenterCarle Foundation HospitalUrbanaUSA
  3. 3.Cytoviva Inc.AuburnUSA
  4. 4.Center for Advanced Radiation SourcesThe University of ChicagoChicagoUSA

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