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Archives of Pharmacal Research

, Volume 39, Issue 9, pp 1232–1236 | Cite as

Flavonol glycosides from the aerial parts of Gynostemma pentaphyllum and their antioxidant activity

  • Hari Jang
  • Jin Woo Lee
  • Chul Lee
  • Qinghao Jin
  • Myung Koo Lee
  • Chong Kil Lee
  • Mi Kyeong Lee
  • Bang Yeon Hwang
Research Article

Abstract

The phytochemical investigation of the aerial parts of Gynostemma pentaphyllum led to the isolation of a new flavonol glycoside, gynopentaphylloside (1), along with seven known compounds (28). The structure of the new compound was determined on the basis of 1D, 2D NMR and HRESIMS data as well as acid hydrolysis. The antioxidant activity of the isolates was evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay.

Keywords

Gynostemma pentaphyllum Cucurbitaceae Flavonol glycoside Antioxidant activity 

Notes

Acknowledgments

This research was financially supported by the Ministry of Trade, Industry & Energy (MOTIE) and Korea Institute for Advancement of Technology (KIAT) through the Inter-ER Cooperation Projects (R0002021). The authors acknowledge the Korea Basic Science Institute for the NMR measurements.

Compliance with ethical standards

Conflict of interest

The authors have declared no conflict of interest.

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Copyright information

© The Pharmaceutical Society of Korea 2016

Authors and Affiliations

  • Hari Jang
    • 1
  • Jin Woo Lee
    • 1
  • Chul Lee
    • 1
  • Qinghao Jin
    • 1
  • Myung Koo Lee
    • 1
  • Chong Kil Lee
    • 1
  • Mi Kyeong Lee
    • 1
  • Bang Yeon Hwang
    • 1
  1. 1.College of PharmacyChungbuk National UniversityCheongjuRepublic of Korea

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