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A new flavonol glycoside from the aerial part of Rudbeckia laciniata

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Abstract

The phytochemical investigation of Rudbeckia laciniata L. obtained a new flavonol glycoside (1), together with four flavonol glycosides (25) and eight quinic acid derivatives (613). The structure was elucidation by means of spectroscopic methods and chemical evidence. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.

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References

  • Ahn, B.G., J.M. Hur, and J.C. Park. 2007. Isolations of flavonoids and a higher alcohol from the aerial parts of Brassica juncea. Korean Journal of Pharmacognosy 38: 254–257.

    CAS  Google Scholar 

  • Barrett, B. 2003. Medicinal properties of Echinacea: A critical review. Phytomedicine 10: 66–86.

    Article  CAS  PubMed  Google Scholar 

  • Basnet, P., K. Matsushige, K. Hase, S. Kadota, and T. Namba. 1996. Four di-O-caffeoyl quinic acid derivatives from propolis potent hepatoprotective activity in experiment liver injury models. Biological and Pharmaceutical Bulletin 19: 1479–1484.

    Article  CAS  PubMed  Google Scholar 

  • Bohlmann, F., J. Jakupovic, and C. Zdero. 1978. Neue norsesquiterpene aus Rudbeckia laciniata und Senecio paludaffinis. Phytochemistry 17: 2034–2036.

    Article  CAS  Google Scholar 

  • Fukushi, Y., C. Yajima, and J. Mizutani. 1994. Prelacinan-7-ol, a novel sesquiterpene from Rudbeckia laciniata. Tetrahedron Letters 35: 8809–8812.

    Article  CAS  Google Scholar 

  • Fukushi, Y., C. Yajima, J. Mizutani, and S. Tahara. 1998. Tricyclic sesquiterpenes from Rudbeckia laciniata in honor of Professor G. H. NEIL TOWERS 75th birthday. Phytochemistry 49: 593–600.

    Article  CAS  Google Scholar 

  • Jakupovic, J., Y. Jia, R.M. King, and F. Bohlmann. 1986. Rudbeckiolid, ein dimeres Sesquiterpenlaction aus Rudbeckia laciniata. Liebigs Annalen der Chemie 8: 1474–1477.

    Article  Google Scholar 

  • Kim, D.K. 2001. Antioxidative compounds from the aerial parts of Lactuca scariola L. Archives of Pharmacal Research 24: 427–430.

    Article  CAS  PubMed  Google Scholar 

  • Kim, K.H., Y.H. Kim, and K.R. Lee. 2007. Isolation of quinic acid derivatives and flavonoids from the aerial parts of Lactuca indica L. and their hepatoprotective activity in vitro. Bioorganic and Medicinal Chemistry Letters 17: 6739–6743.

    Article  CAS  PubMed  Google Scholar 

  • Latza, S., D. Ganber, and R.G. Berger. 1996. Carbohydrated esters of cinnamic acid from fruits of Physalis Peruviana, Psidium Guajava, and Vaccinium vitis-Idaea. Phytochemisty 43: 481–485.

    Article  CAS  Google Scholar 

  • Lee, S.Y., K.W. Woo, C.S. Kim, D.U. Lee, and K.R. Lee. 2013. New lignans from the aerial parts of Rudbeckia laciniata. Helvetica Chimica Acta 96: 320–325.

    Article  CAS  Google Scholar 

  • Lee, T.B. 2003. Coloured flora of Korea, 350. Seoul: Hyang-Moon Publishing Co.

    Google Scholar 

  • Mabry, T.J., K.R. Markham, and B.M. Thomas. 1970. The systematic identification of flavonoids, Chapter 5, 39–61. New York: Springer.

    Book  Google Scholar 

  • Nunes, F.M., A. Reis, A.M.S. Silva, M. Rosario, M. Domingues, and M.A. Coimbra. 2008. Rhamnoarabinosyl and rhamnoarabinoarabinosyl side chains as structural features of coffee arabinogalactans. Phytochemisty 69: 1573–1585.

    Article  CAS  Google Scholar 

  • Skehan, P., R. Storeng, D. Scudiero, A. Monks, J. Mcmahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, and M.R. Boyd. 1990. New colorimetric cytotoxicity assay for anticancer-drug screening. Journal of the National Cancer Institute 82: 1107–1112.

    Article  CAS  PubMed  Google Scholar 

  • Takemura, M., R. Nishida, N. Mori, and Y. Kuwahara. 2002. Acylated flavonol glycosides as probing stimulants of a bean aphid, Megoura crassicauda, from Vicia angustifolia. Phytochemistry 61: 135–140.

    Article  CAS  PubMed  Google Scholar 

  • Yeom, S.H., M.K. Kim, H.J. Kim, J.G. Shim, J.H. Lee, and M.W. Lee. 2003. Phenolic compounds from seeds of Astragalus sinicus and its antioxidative activities. Korean Journal of Pharmacognosy 34: 344–351.

    CAS  Google Scholar 

  • Young, H.S., J.C. Park, H.J. Park, J.H. Lee, and J.S. Choi. 1991. Phenolic compounds of the leaves of Eucommia ulmoides. Archives of Pharmacal Research 14: 114–117.

    Article  Google Scholar 

  • Zahid, M., A. Ali, O. Ishurd, A. Ahmed, Z. Ali, V.U. Ahmed, and Y. Pan. 2002. New cycloartane and flavonol glycosides from Corchorus depressus. Helvetica Chimica Acta 85: 689–697.

    Article  CAS  Google Scholar 

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Acknowledgments

This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (20110028285). The authors would like to thank Mr. Do Kyun Kim, Dr. Eun Jung Bang, and Dr. Jung Ju Seo at the Korea Basic Science Institute for the NMR and MS spectra measurements.

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Correspondence to Kang Ro Lee.

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Lee, S.Y., Shin, Y.J., Choi, S.U. et al. A new flavonol glycoside from the aerial part of Rudbeckia laciniata . Arch. Pharm. Res. 37, 834–838 (2014). https://doi.org/10.1007/s12272-013-0199-y

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