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Constituents of the root of Anemone tomentosa

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Abstract

A new diterpene glycoside, tomentoside I (1), along with eleven known compounds, including the four coumarins, 4,5-dimethoxyl-7-methylcoumarin (2), 4,7-dimethoxyl-5-methylcoumarin (3), isofraxidin (4) and fraxidin (5) as well as the seven triterpenoids, oleanolic acid (6), oleanolic acid 3-O-α-L-arabinopyranoside (7), oleanolic acid 3-O-β-D-galactopyranosyl-(1→3)-β-D-glucopyranoside (8), hederagenin 3-O-α-L-arabinopyranoside (9), betulinic acid (10), 18-hydroxyursolic acid (11) and 2α,3β,23-trihydroxyurs-12-en-28-oic acid (12) were isolated from the ethanolic extract of the root of Anemone tomentosa and their chemical structures were elucidated by spectroscopic methods. The antimicrobial activities of compounds 1–12 were measured using the agar disc-diffusion method. Also, their antioxidant activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) were evaluated.

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Longdong University, Qingyang, 745000, Gansu, China

    Hao-Bin Hu, Xu-Dong Zheng, Yu-Feng Jian, Jian-Xin Liu & Ji-Hua Zhu

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  1. Hao-Bin Hu
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  2. Xu-Dong Zheng
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  3. Yu-Feng Jian
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Correspondence to Hao-Bin Hu.

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Hu, HB., Zheng, XD., Jian, YF. et al. Constituents of the root of Anemone tomentosa . Arch. Pharm. Res. 34, 1097–1105 (2011). https://doi.org/10.1007/s12272-011-0707-x

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  • DOI: https://doi.org/10.1007/s12272-011-0707-x

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