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An anti-influenza component of the bark of Alnus japonica


This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (14) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.

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Correspondence to Young Ho Kim.

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Tung, N.H., Kwon, HJ., Kim, JH. et al. An anti-influenza component of the bark of Alnus japonica . Arch. Pharm. Res. 33, 363–367 (2010).

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Key words

  • Alnus japonica
  • Betulaceae
  • Lupane triterpene
  • Anti-influenza
  • KBNP-0028