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Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol

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  • Drug Efficacy and Safety
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Abstract

Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.

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Correspondence to Eun-Hee Park.

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Jung, HJ., Song, Y.S., Lim, CJ. et al. Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol. Arch. Pharm. Res. 31, 1275–1279 (2008). https://doi.org/10.1007/s12272-001-2106-1

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  • DOI: https://doi.org/10.1007/s12272-001-2106-1

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