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Komplexe siRNA-Pools erzeugen optimales Gen-Silencing

  • Anwendungen & Produkte
  • RNA-Interferenz
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BIOspektrum Aims and scope

Abstract

Differences in the silencing efficiency of siRNAs for the same target gene affect the interpretability of RNAi experiments. The best way to ensure consistent and optimal gene silencing is to use a complex pool of siRNAs (siPOOLs).

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Literatur

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Author information

Authors and Affiliations

  1. siTOOLs Biotech GmbH, Lochhamerstraße 29a, D-82152, Planegg, Deutschland

    Andrew Walsh, Kevin Wobedo &  Michael Hannus

  2. Biozym Scientific GmbH, Steinbrinksweg 27, D-31840, Hess.-Oldendorf, Deutschland

    Monika Burbach

  3. Lehrstuhl für Biochemie I, Fakultät für Biologie und Vorklinische Medizin, Universität Regensburg, Universitätsstraße 31, D-93053, Regensburg, Deutschland

    Gunter Meister

Authors
  1. Andrew Walsh
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  2. Kevin Wobedo
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  3. Monika Burbach
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  4. Michael Hannus
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  5. Gunter Meister
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Corresponding authors

Correspondence to Andrew Walsh, Monika Burbach, Michael Hannus or Gunter Meister.

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Walsh, A., Wobedo, K., Burbach, M. et al. Komplexe siRNA-Pools erzeugen optimales Gen-Silencing. Biospektrum 30, 302–304 (2024). https://doi.org/10.1007/s12268-024-2202-1

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  • DOI: https://doi.org/10.1007/s12268-024-2202-1

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