Skip to main content
SpringerLink
Log in

Rekonstruktion mikrobieller Evolution durch Sequenzierung alter DNA

  • Wissenschaft · Special: Next Generation Sequencing
  • Paläogenomik
  • Published:
BIOspektrum Aims and scope

Abstract

The study of human pathogens, their genomes and their evolution has been revolutionized by the introduction of ancient DNA techniques both in the lab and in silico. Today, palaeogenomic research can reconstruct microbial genomes starting from as much as a couple of reads detected during screenings. With every year, the number of organisms and genomes increases, and with it the field’s power to answer a wide range of questions pertaining to the evolution and the dynamics of studied pathogens.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Spyrou MA, Bos KI, Herbig A et al. (2019) Ancient pathogen genomics as an emerging tool for infectious disease research. Nat Rev Genet 20: 323–340

    Article  CAS  Google Scholar 

  2. Guellil M, Keller M, Dittmar JM et al. (2022) An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon Plague victim. Genome Biol 23: 22

    Article  CAS  Google Scholar 

  3. Houldcroft CJ, Beale MA, Breuer J (2017) Clinical and biological insights from viral genome sequencing. Nat Rev Microbiol. 15: 183–192

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Estonian Biocentre, Institute of Genomics, University of Tartu, Riia 23b, 51010, Tartu, Estland

    Meriam Guellil & Marcel Keller

  2. Abteilung Anthropologie, Institut für Rechtmedizin, Universität Bern, Bern, Schweiz

    Marcel Keller

Authors
  1. Meriam Guellil
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marcel Keller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Meriam Guellil.

Additional information

Danksagung

Die Autoren danken dem Estonian Research Council für finanzielle Unterstützung im Rahmen des Projekts PRG1027.

Meriam Guellil 2008–2012 Archäologie- (BA) und Biologiestudium an der Universität Wien, Österreich. 2012–2013 Masterstudium in Osteologie (Msc) an der Universität Sheffield, UK. Anschließend Research Associate an der Universität York gefolgt von einem Doktoratstudium an der Universität Oslo, Norwegen. 2018 Promotion in Genomik. Seit 2018 Postdoc am Institut für Genomik der Universität Tartu, Estland.

Marcel Keller 2008–2013 Studium der Biologie (BSc, MSc) an der LMU München, anschließend Doktorand am Dept. Archäogenetik, Max-Planck-Institut für Menschheitsgeschichte, Jena. 2020 Promotion an der Universität Jena. Seit 2019 Postdoc am Institute of Genomics der Universität Tartu, Estland. Seit 2022 Wissenschaftlicher Mitarbeiter am Dept. Anthropologie, Institut für Rechtsmedizin, Universität Bern, Schweiz.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Guellil, M., Keller, M. Rekonstruktion mikrobieller Evolution durch Sequenzierung alter DNA. Biospektrum 28, 287–290 (2022). https://doi.org/10.1007/s12268-022-1766-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12268-022-1766-x

Search

Navigation