Abstract
Intracellular pathogens thrive by invading host cells, thereby creating protected replicative niches. The manipulation of host cells is accomplished by means of translocated bacterial effector proteins. The ability to track effector proteins during an infection is essential to understand host-pathogen interaction. Here, we describe a novel method to target bac terial effector proteins using Salmonella enterica as a model organism and deploying self-labeling enzyme tags.
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Vera Göser 2008-2015 Biologie- (B. Sc.) und Mikrobiologiestudium (M. Sc.) an der Universität Bonn. 2015-2019 Promotion an der Universität Osnabrück in der Abteilung Mikrobiologie bei Prof. Dr. M. Hensel.
Michael Hensel Jahrgang 1962. 1982-1988 Biologiestudium an der Universität Osnabrück, dort 1989-1993 Promotion in Mikrobiologie. 1993-1996 Post-doc bei Prof. Dr. D. Holden, Imperial College London, UK. 1996-2000 Gruppenleiter bei Prof. Dr. J. Heesemann am Max-von-Pettenkofer-Insti-tut, LMU München. 2000-2009 C3/W2-Profes-sur an der Universität Erlangen-Nürnberg. Seit 2009 W3-Professur und Leitung der Abt. Mikrobiologie, Fachbereich Biologie/Chemie, Universität Osnabrück.
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Göser, V., Hensel, M. Translokation bakterieller Effektorproteine — live und in Farbe. Biospektrum 25, 727–731 (2019). https://doi.org/10.1007/s12268-019-1305-6
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DOI: https://doi.org/10.1007/s12268-019-1305-6