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BIOspektrum

, Volume 25, Issue 3, pp 338–339 | Cite as

Organisch-chemisch stabilisierte Enzyme für eine nachhaltige Wirtschaft

  • Saskia Neubacher
  • Sven Hennig
  • Tom N. GrossmannEmail author
Open Access
Biotechnologie Enzymtechnologie

Abstract

Advances in protein engineering have made the industrial use of enzymes feasible, though, a more wide-spread application is hampered by the limited stability of enzymes under often required harsh conditions. We developed a protein stabilization technology that involves the in situ cyclization of proteins (INCYPRO) and facilitates the design and semi-synthesis of multicyclic enzymes. These synthetically enhanced durable enzymes add to the current efforts towards a sustainable and green economy.

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Copyright information

© Die Autoren 2019

Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, duplication, adaption, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Open access funding provided by Vrije Universiteit Amsterdam, The Netherlands.

Authors and Affiliations

  • Saskia Neubacher
    • 1
  • Sven Hennig
    • 1
  • Tom N. Grossmann
    • 1
    Email author
  1. 1.Department of Chemistry and Pharmaceutical SciencesVrije Universiteit AmsterdamAmsterdamNiederlande

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