, Volume 25, Issue 3, pp 338–339 | Cite as

Organisch-chemisch stabilisierte Enzyme für eine nachhaltige Wirtschaft

  • Saskia Neubacher
  • Sven Hennig
  • Tom N. GrossmannEmail author
Open Access
Biotechnologie Enzymtechnologie


Advances in protein engineering have made the industrial use of enzymes feasible, though, a more wide-spread application is hampered by the limited stability of enzymes under often required harsh conditions. We developed a protein stabilization technology that involves the in situ cyclization of proteins (INCYPRO) and facilitates the design and semi-synthesis of multicyclic enzymes. These synthetically enhanced durable enzymes add to the current efforts towards a sustainable and green economy.


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Copyright information

© Die Autoren 2019

Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits use, duplication, adaption, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Open access funding provided by Vrije Universiteit Amsterdam, The Netherlands.

Authors and Affiliations

  • Saskia Neubacher
    • 1
  • Sven Hennig
    • 1
  • Tom N. Grossmann
    • 1
    Email author
  1. 1.Department of Chemistry and Pharmaceutical SciencesVrije Universiteit AmsterdamAmsterdamNiederlande

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