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BIOspektrum

, Volume 24, Issue 3, pp 260–263 | Cite as

Genetische Aspekte bei Alkoholismus

  • Jens Treutlein
  • Rainer Spanagel
Wissenschaft Personalisierte Medizin
  • 30 Downloads

Abstract

Studies in twins demonstrate major genetic influences in the development of alcohol use disorders (AUD) such as addiction. Candidate studies and genome-wide association studies (GWAS) have identified numerous candidate genes for excessive alcohol consumption and AUD. Here we present a convergent functional genetics approach which is a translational methodology that integrates multiple lines of evidence from studies in human and animal models to get a better understanding of the genetics of AUD.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Abteilung für Genetische Epidemiologie in der Psychiatrie, Zentralinstitut für Seelische Gesundheit, Medizinische FakultätMannheim der Universität HeidelbergHeidelbergDeutschland
  2. 2.Institut für Psychopharmakologie, Zentralinstitut für Seelische Gesundheit, Medizinische FakultätMannheim der Universität HeidelbergHeidelbergDeutschland
  3. 3.Zentralinstitut für Seelische Gesundheit Medizinische FakultätMannheim der Universität Heidelberg, J5MannheimDeutschland

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