Abstract
Electrode-assisted fermentation is a new strategy in anaerobic biotechnology. It can be used for reactions in which the average oxidation state of the end product is higher than the substrate. Here we show two applications of an electrode-assisted fermentation for the anoxic production of acetoin. The presented approaches in Shewanella oneidensis and Escherichia coli utilize engineered metabolisms to achieve high product yields of roughly 80 percent under strictly anoxic conditions.
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Literatur
Statistisches Bundesamt (2017) Fachserie 4, Produzie - rendes Gewerbe. Reihe 3.1 – 2016, Produktion im produzierenden Gewerbe. Produktion im produzierenden Gewerbe, www.destatis.de/DE/Publikationen/Thematisch/IndustrieVerarbeitendesGewerbe/Konjunkturdaten/IndexProduktion2040210172114.pdf?__blob=publicationFile
Prognos AG (2017) Die deutsche chemische Industrie 2030–Update 2015/2016. Verband der chemischen Industrie e. V. (VCI), Frankfurt
van Haveren J, Scott EL, Sanders J (2008) Bulk chemicals from biomass. Biofuels Bioprod Biorefin 2:41–57
Shin JH, Kim HU, Kim DI et al. (2013) Production of bulk chemicals via novel metabolic pathways in microorganisms. Biotechnol Adv 31:925–935
Weusthuis RA, Lamot I, van der Oost J et al. (2011) Microbial production of bulk chemicals: development of anaerobic processes. Trends Biotechnol 29:153–158
Werpy TA, Holladay JE, White JF (2004) Top Value Added Chemicals from Biomass: I. Results of Screening for Potential Candidates from Sugars and Synthesis Gas. Pacific Northwest National Laboratory (PNNL), Richland, WA, USA
Bursac T, Gralnick JA, Gescher J (2017) Acetoin production via unbalanced fermentation in Shewanella oneidensis. Biotechnol Bioeng 114:1283–1289
Förster AH, Beblawy S, Golitsch F et al. (2017) Electrode-assisted acetoin production in a metabolically engineered Escherichia coli strain. Biotechnol Biofuels 10:65
Sturm-Richter K, Golitsch F, Sturm G et al. (2015) Unbalanced fermentation of glycerol in Escherichia coli via heterologous production of an electron transport chain and electrode interaction in microbial electrochemical cells. Bioresour Technol 186:89–96
Yang T, Rao Z, Zhang X et al. (2017) Metabolic engineering strategies for acetoin and 2,3-butanediol production: advances and prospects. Crit Rev Biotechnol 37:990–1005
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Beblawy, S., Bursac, T. & Gescher, J. Elektrofermentation von Acetoin. Biospektrum 24, 100–103 (2018). https://doi.org/10.1007/s12268-018-0893-x
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DOI: https://doi.org/10.1007/s12268-018-0893-x