Automatisiertes Klonscreening und Vorhersage der Expressionsleistung
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Directed evolution of proteins provides millions of potentially interesting variants that have to be cultured and screened. To handle this experimental effort, high-throughput screening systems are needed. Nevertheless, these systems are often error-proned due to the lack of online monitoring tools. This gap is closed by additional optical measurement systems that allow a control of the whole process and a prediction of expression performance without using off-line assays.
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