BIOspektrum

, Volume 24, Issue 1, pp 46–49 | Cite as

Automatisiertes Klonscreening und Vorhersage der Expressionsleistung

Wissenschaft · Special: Liquid Handling & Probenvorbereitung Robotik in der Biotechnologie
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Abstract

Directed evolution of proteins provides millions of potentially interesting variants that have to be cultured and screened. To handle this experimental effort, high-throughput screening systems are needed. Nevertheless, these systems are often error-proned due to the lack of online monitoring tools. This gap is closed by additional optical measurement systems that allow a control of the whole process and a prediction of expression performance without using off-line assays.

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Copyright information

© Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Aachener Verfahrenstechnik (AVT) Lehrstuhl für BioverfahrenstechnikRWTH AachenAachenDeutschland

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