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Cohesin – ein Proteinring für Genomstabilität und Chromatinfaltung

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  • Genregulation und Chromatinorganisation
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BIOspektrum Aims and scope

Abstract

The cohesin complex has evolved as major player for structuring the chromatin fiber with roles in chromosome segregation, chromatin architecture, DNA damage repair and gene regulation. This article summarizes the latest discoveries and models for cohesin function and also reviews implications of the cohesin complex in developmental syndromes and cancer.

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Authors and Affiliations

  1. Abteilung Zellbiologie, Erasmus MC Faculty building Ee10.20, Erasmus Medical Center, Wytemaweg 80, NL-3015CN, Rotterdam, Niederlande

    Kerstin S. Wendt

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  1. Kerstin S. Wendt
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Correspondence to Kerstin S. Wendt.

Additional information

Kerstin S. Wendt Jahrgang 1973. 1993–1998 Biochemiestudium an der Universität Leipzig. 1998–2002 Anfertigung der Dissertation in der Abteilung Strukturbiologie am Max-Planck-Institut für Biochemie, Martinsried, und 2002 Promotion (Dr. rer. nat.) an der TU München. 2003–2008 Postdoc am Research Institute of Molecular Pathology (IMP) in Wien, Österreich. Seit 2009 Arbeitsgruppenleiterin (Cohesin and Chromatin Structure Group) in der Abteilung Zellbiologie am Erasmus Medical Center in Rotterdam, Niederlande.

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Wendt, K.S. Cohesin – ein Proteinring für Genomstabilität und Chromatinfaltung. Biospektrum 23, 519–521 (2017). https://doi.org/10.1007/s12268-017-0834-0

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  • DOI: https://doi.org/10.1007/s12268-017-0834-0

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