Advertisement

BIOspektrum

, Volume 23, Issue 4, pp 424–426 | Cite as

Peptidliganden zur Aufreinigung kamelider Schwere-Ketten-Antikörper

Methoden der Proteinchemie
  • Matthias Paschke
  • Veit Althoff
Anwendungen & Produkte

Abstract

Highly specific peptides that bind a given target protein are useful ligands for the affinity purification of such proteins from complex biological matrices. The capability to provide this kind of peptidic ligands for the affinity purification of virtually any protein can simplify and enhance the downstream process development. The general applicability, scalability, and comparatively low costs of peptidic ligands are key features for their application in downstream purification processes.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. [1]
    Muyldermans S (2001) Single domain camel antibodies: current status. J Biotechnol 74:277–302PubMedGoogle Scholar
  2. [2]
    Teillaud JL (2012) From whole monoclonal antibodies to single domain antibodies: think small. Methods Mol Biol 911:3–13PubMedGoogle Scholar
  3. [3]
    De Genst E, Saerens D, Muyldermans S et al. (2006) Antibody repertoire developement in camelids. Dev Comp Immunol 30:187–198CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Deutschland 2017

Authors and Affiliations

  1. 1.3B PharmaceuticalsBerlinDeutschland
  2. 2.Knauer Wissenschaftliche Geräte GmbHBerlinDeutschland

Personalised recommendations