Abstract
Single-cell analysis emerged as a promising tool to analyze the heterogeneity of complex cell populations by characterizing each individual cell. Conventional isolation workflows or instruments are often not able to isolate both eukaryotic and prokaryotic cells or require complex and costintensive devices. The single-cell printer (SCP)–an instrument for automated single-cell isolation and deposition–allows precise cell deposition for subsequent molecular analyses on the single-cell level, and efficient clonal cell line development.
Similar content being viewed by others
Literatur
Gross A, Schoendube J, Zimmermann S et al. (2015) Technologies for single-cell isolation. Int J Mol Sci 16:16897–16919
Gross A, Schondube J, Niekrawitz S et al. (2013) Singlecell printer: automated, on demand, and label free. J Lab Autom 18:504–518
Riba J, Gleichmann T, Zimmermann S et al. (2016) Labelfree isolation and deposition of single bacterial cells from heterogeneous samples for clonal culturing. Sci Rep 6:32837
Huang L, Ma F, Chapman A et al. (2015) Single-cell wholegenome amplification and sequencing: methodology and applications. Annu Rev Genomics Hum Genet 16:79–102
Riba J, Renz N, Niemöller C et al. (2016) Molecular genetic characterization of individual cancer cells isolated via singlecell printing. PLoS One 11:e0163455
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Riba, J., Zimmermann, S., Steimle, B. et al. Vereinzelung von prokaryotischen und eukaryotischen Zellen. Biospektrum 23, 298–300 (2017). https://doi.org/10.1007/s12268-017-0799-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12268-017-0799-z