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Fluoreszierende Proteinsensoren für die Redoxregulation in lebenden Zellen

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  • In vivo-Biosensoren
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Abstract

Redox signalling is increasingly recognized to play a crucial role in cellular and organismal physiology. Whilst we have made considerable advances in recent years with respect to understanding the roles and regulation of many different cellular redox species, research remains restricted by a lack of appropriate tools and techniques. Here we discuss the opportunities afforded by recently developed genetically encoded redox sensors and illustrate how they have already advanced our understanding.

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Authors and Affiliations

  1. Zelluläre Biochemie, Technische Universität Kaiserslautern, Erwin-Schrödinger-Straße 13, D-67663, Kaiserslautern, Deutschland

    Bruce Morgan

  2. Plant Energy Biology Lab, Institut für Nutzpflanzenwissenschaften und Ressourcenschutz (INRES) - Chemical Signalling, Rheinische Friedrich-Wilhelms-Universität Bonn, Friedrich-Ebert-Allee 144, D-53113, Bonn, Deutschland

    Markus Schwarzländer

Authors
  1. Bruce Morgan
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  2. Markus Schwarzländer
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Corresponding authors

Correspondence to Bruce Morgan or Markus Schwarzländer.

Additional information

Bruce Morgan Jahrgang 1980. Mikrobiologiestudium an der University of Wales in Cardiff, UK. 2007 Promotion an der University of Manchester, UK. 2008–2009 wissenschaftlicher Mit arbeiter. 2010–2014 wissenschaftlicher Mitarbeiter am Deutschen Krebsforschungszentrum (DKFZ), Heidelberg. 2015 Gruppenleiter in Zellulärer Biochemie, TU Kaisers lautern.

Markus Schwarzländer Jahrgang 1982. Chemie- und Biochemiestudium an der LMU München. 2009 Promotion an der University of Oxford, UK. 2009–2011 Weston Junior Research Fellow am Department of Plant Sciences und New College, University of Oxford. 2011–2013 wissenschaftlicher Mitarbeiter an der Universität Bonn; dort seit 2013 Emmy Noether-Nachwuchsgruppenleiter in Plant Energy Biology.

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Morgan, B., Schwarzländer, M. Fluoreszierende Proteinsensoren für die Redoxregulation in lebenden Zellen. Biospektrum 22, 260–263 (2016). https://doi.org/10.1007/s12268-016-0683-2

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  • DOI: https://doi.org/10.1007/s12268-016-0683-2

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