Abstract
Paramutation refers to an allelic interaction, whereby the paramutagenic allele of a gene induces a heritable change of expression at a paramutable allele. The paramutated allele becomes paramutagenic itself. Paramutation is an example that acquired states of gene expression can be inherited. Originally discovered in plants, it can also occur in other organisms. It is mechanistically connected to important epigenetic regulatory pathways and potentially relevant for evolution and population genetics.
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Jasmin Bassler 2006–2010 Biotechnologiestudium an der Fachhochschule FH Campus Wien, Österreich. Diplomarbeit am Gregor Mendel Institut für Molekulare Pflanzenbiologie, Wien. 2010–2013 Studium der Publizistik- und Kommunikationswissenschaften an der Universität Wien. Seit 2012 Promotion im Doktoratskolleg Chromosome Dynamics am Gregor Mendel Institut für Molekulare Pflanzenbiologie.
Ortrun Mittelsten Scheid 1975–1985 Biologiestudium und Promotion an der Universität Hamburg. 1986–1987 Postdoc am Max-Planck-Institut für Zellbiologie, Ladenburg. 1988–1992 Postdoc an der ETH Zürich, Schweiz. 1992–2003 Postdoc am Friedrich Miescher Institut, Basel, Schweiz. Seit 2004 Gruppenleiterin am Gregor Mendel Institut für Molekulare Pflanzenbiologie, Wien, Österreich.
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Bassler, J., Mittelsten Scheid, O. Paramutation: eine Begegnung mit bleibendem Eindruck. Biospektrum 22, 128–130 (2016). https://doi.org/10.1007/s12268-016-0663-6
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DOI: https://doi.org/10.1007/s12268-016-0663-6