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Bakterielle Megastädte

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  • 3D-Architektur von Biofilmen
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Abstract

What makes a multicellular aggregate of bacterial cells a biofilm is the presence of an extracellular polymeric matrix. Besides being protective, matrix components such as amyloid curli fibres and cellulose in Escherichia coli also assemble into a complex architecture that is controlled by RpoS and c-di-GMP. This confers extreme cohesion and elasticity to macrocolony biofilms. As a consequence, these biofilms behave like tissues, i. e. they buckle up into intricate morphological structures during growth.

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Authors and Affiliations

  1. Institut für Biologie/Mikrobiologie, Humboldt-Universität zu Berlin, Chaußseestraße 117, D-10115, Berlin, Germany

    Regine Hengge

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  1. Regine Hengge
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Correspondence to Regine Hengge.

Additional information

Regine Hengge 1976–1986 Biologiestudium (Diplom) und Promotion an der Universität Konstanz. 1987–1988 Postdoc-Aufenthalt an der Princeton University, NJ, USA. 1994 Habilitation in Mikrobiologie und Molekularer Genetik und C2-Dozentur an der Universität Konstanz. 1998–2013 C4-Professur an der FU Berlin. Seit 2013 W3-Professur an der HU Berlin

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Hengge, R. Bakterielle Megastädte. Biospektrum 21, 480–483 (2015). https://doi.org/10.1007/s12268-015-0603-x

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  • DOI: https://doi.org/10.1007/s12268-015-0603-x

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