Abstract
Natural nicotinamide cofactors (NAD(P)) can in some cases be replaced by simple synthetic analogues (mNADs). These analogues can enable ‘faster than naturally designed’ enzymatic reactions, more efficient reaction processes and more chemoselective reactions because of their bioorthogonality.
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Caroline E. Paul Jahrgang 1985. Studium der Biologischen Chemie an der Universität von Toronto, Kanada. 2013 Promotion an der Universität von Oviedo, Spanien. Seit 2013 Marie-Curie-Postdoc in der Arbeitsgruppe von Dr. F. Hollmann an der Technischen Universität Delft, Niederlande.
Frank Hollmann Jahrgang 1973. Chemiestudium an der Universität Bonn. 2004 Promotion an der Eidgenössischen Technischen Hochschule Zürich, Schweiz. 2004–2005 Postdoc am Max-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr. 2005–2008 Gruppenleiter Biokatalyse bei Evonik, Essen. Seit 2008 Assistant Professor an der Technischen Universität Delft, Niederlande.
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Hollmann, F., Paul, C.E. Synthetische Nikotinamide in der Biokatalyse. Biospektrum 21, 376–378 (2015). https://doi.org/10.1007/s12268-015-0587-6
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DOI: https://doi.org/10.1007/s12268-015-0587-6