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Antibakterielle Strategien und bakterielle Abwehrmechanismen

Abstract

In the face of multi-resistant pathogens it is time to find new antibacterial strategies. A system-based approach to studying antibiotic action of natural compounds, antimicrobial peptides, and small molecules allows investigation of clinically unexploited antibiotic classes and targets as well as intrinsic bacterial defence mechanisms. We also investigate the antibacterial activity and mechanisms of action of technical plasmas (ionized gases). They are promising wound disinfectants, which are in clinical development to complement established antibiotic approaches.

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Correspondence to Sina Langklotz or Julia E. Bandow.

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Julia Bandow Jahrgang 1975. Biologiestudium an der Universität Greifswald. 2002 Promotion. 2002–2008 Wissenschaftlerin bei Pfizer Global Research and Development, Ann Arbor, MI, USA. 2008–2014 Juniorprofessorin für Mikrobielle Antibiotikaforschung an der Universität Bochum. Seit 2014 Leiterin der AG Angewandte Mikrobiologie an der Universität Bochum. Im Rahmen der VAAM-Jahresstagung in Dresden mit dem VAAM-Forschungspreis 2014 ausgezeichnet.

Sina Langklotz Jahrgang 1982. Biologiestudium an der Universität Bochum. 2011 Promotion. Seit 2012 Postdoc in der AG Angewandte Mikrobiologie an der Universität Bochum.

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Langklotz, S., Bandow, J.E. Antibakterielle Strategien und bakterielle Abwehrmechanismen. Biospektrum 20, 744–746 (2014). https://doi.org/10.1007/s12268-014-0512-4

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  • DOI: https://doi.org/10.1007/s12268-014-0512-4