, Volume 20, Issue 4, pp 460–463 | Cite as

Vom Fed-Batch-Screening bis zur chiralen Analytik

  • Thomas GrimmEmail author
  • Peter NeubauerEmail author
Biotechnologie Biokatalyse


An efficient screening system could be established, which allows a fast test of microbial strain collections for new catalytic activities. This was developed by the combination of methods of the high-cell-density cultivation with on-line sensors followed by whole cell biotransformation with chiral gas chromatography. Here we describe the application of the system in a screening with different yeasts for the biotransformation of chiral alcohols.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Fachgebiet Bioverfahrenstechnik, Institut Für BiotechnologieTU BerlinBerlinGermany
  2. 2.BioworxBerlinGermany
  3. 3.Fachgebiet Bioverfahrenstechnik Institut für BiotechnologieTechnische Universität BerlinBerlinGermany
  4. 4.BIOWORXBerlinGermany

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