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BIOspektrum

, Volume 20, Issue 4, pp 404–406 | Cite as

Humane 3D-in vitro-Testsysteme für die präklinische Forschung

  • Angela Rossi
  • David Fecher
  • Sebastian Egner
  • Matthias Schweinlin
  • Maria Steinke
  • Heike WallesEmail author
Wissenschaft · Special: Zellbiologie Bioassays
  • 109 Downloads

Abstract

In vitro test systems have to be optimized to reduce preclinical failure rates. Therefore, we have introduced a new innovative system which mimics physiological conditions and enables vascularisation in bioreactors. Thus, we have developed test systems for intestinal uptake studies, for airway infections and for different tumour entities, e. g. lung cancer. A further approach presents the ex vivo cornea test system for irritation studies.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Angela Rossi
    • 1
  • David Fecher
    • 1
  • Sebastian Egner
    • 1
  • Matthias Schweinlin
    • 1
  • Maria Steinke
    • 1
  • Heike Walles
    • 2
    Email author
  1. 1.Lehrstuhl für Tissue Engineering und Regenerative MedizinUniversitätsklinikumWürzburgGermany
  2. 2.Universitätsklinikum Würzburg Lehrstuhl für Tissue Engineering und Regenerative Medizin Fraunhofer-Projektgruppe „Regenerative Technologien in der Onkologie“WürzburgGermany

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