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BIOspektrum

, Volume 20, Issue 4, pp 376–379 | Cite as

Molekulare Thermometer zur Steuerung der Virulenz von Yersinia

  • Ann Kathrin Heroven
  • Petra DerschEmail author
Wissenschaft Bakterielle Protein- und RNA-Thermometer
  • 43 Downloads

Abstract

The ability to sense the temperature of surrounding environments is a prerequisite for many bacterial pathogens to adjust their virulence program to establish an infection. Pathogenic Yersinia species use intrinsic thermosensing protein domains and mRNA secondary structures of crucial virulence regulators to activate essential colonization factors during the early infection stage and induce antiphagocytic strategies to prevent attacks of the innate host immune system during the ongoing infection.

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Literatur

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Abteilung für Molekulare InfektionsbiologieHelmholtz-Zentrum für InfektionsforschungBraunschweigGermany
  2. 2.Abt. Molekulare InfektionsbiologieHelmholtz-Zentrum für Infektionsforschung (HZI)BraunschweigGermany

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