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Identifikation neuartiger Halohydrin-Dehalogenasen

  • Biotechnologie
  • Biokatalyse
  • Published:
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Abstract

Halohydrin dehalogenases (HHDHs) are biotechnologically relevant enzymes that can be applied as biocatalysts for the selective synthesis of various β-substituted alcohols. Despite that fact, only very few HHDHs are currently available. In an attempt to identify novel ones, database mining of publicly available sequence databases was performed using HHDH-specific sequence information. As a result, 19 novel HHDHs were obtained all exhibiting true HHDH activity.

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Authors and Affiliations

  1. Institut Für Biotechnologie, Rwth Aachen, Aachen, Germany

    Anett Schallmey

  2. IBG-1, Forschungszentrum Jülich Gmbh, Jülich, Germany

    Marcus Schallmey

  3. Enzymicals Ag, Greifswald, Germany

    Rainer Wardenga

  4. Juniorprofessur für Biokatalyse, Institut für Biotechnologie RWTH Aachen, Worringerweg 3, D-52074, Aachen, Germany

    Anett Schallmey

Authors
  1. Anett Schallmey
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  2. Marcus Schallmey
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  3. Rainer Wardenga
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Correspondence to Anett Schallmey.

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Schallmey, A., Schallmey, M. & Wardenga, R. Identifikation neuartiger Halohydrin-Dehalogenasen. Biospektrum 19, 816–817 (2013). https://doi.org/10.1007/s12268-013-0394-x

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  • DOI: https://doi.org/10.1007/s12268-013-0394-x

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