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Bakterielle proteintoxine: Waffen gegen konkurrenten

Colicine

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Abstract

Bacteriocins are bacterial protein toxins that kill competitors for the same ecological niche. Bacterial toxins are enzymes or pore-forming proteins which are equipped with receptor binding and translocation domains bringing the activity domains into cells. Those which are formed by Escherichia coli are named colicins. Nearly 50 percent of natural E. coli isolates produce colicins. They are actively taken up by E. coli through sophisticated mechanisms and kill cells by various means.

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Correspondence to Volkmar Braun.

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Volkmar Braun Chemiestudium an den Universitäten Freiburg und München. 1965 Promotion am MPI für Biochemie in München. 1966–1971 Postdoc am California Institute of Technology in Pasadena, CA, USA, und am MPI für Biologie in Tübingen. 1972–1974 Leiter einer selbstständigen Arbeitsgruppe am MPI für Molekulare Genetik in Berlin. 1974 Lehrstuhl für Mikrobiologie an der Universität Tübingen. Seit 2007 Max Planck Fellow am MPI für Entwicklungsbiologie in Tübingen.

Silke I. Patzer Biochemiestudium an der Universität Tübingen und am MPI für Biochemie in Martinsried. Diplomarbeit am MPI für Biologie in Tübingen. 1999 Promotion an der Universität Tübingen. Bis 2007 wissenschaftliche Mitarbeiterin am MPI für Biologie in Tübingen und an der Universität Tübingen. Seit 2007 wissenschaftliche Mitarbeiterin am MPI für Entwicklungsbiologie in Tübingen.

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Braun, V., Patzer, S.I. Bakterielle proteintoxine: Waffen gegen konkurrenten. Biospektrum 19, 22–24 (2013). https://doi.org/10.1007/s12268-013-0264-6

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  • DOI: https://doi.org/10.1007/s12268-013-0264-6

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