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Einwegsysteme in zellkulturbasierten Herstellprozessen für Biopharmazeutika

Bioprozesstechnik

  • Biotechnologie
  • Published:
BIOspektrum Aims and scope

Abstract

Production of biopharmaceuticals from mammalian cells is classically performed using stainless-steel tanks and pipes for cell culture, purification and fill and finish. Recently, disposable systems have been used successfully along the entire process flow up to the 2.000 l scale. It will be crucial to characterize these systems further in particular to ensure a profound process understanding and reliable transfer between stainless-steel and fully disposable facilities.

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Literatur

  1. Singh V (1999) Disposable bioreactor for all cell culture using wave-induced agitation. Cytotechnology 30:149–158

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Author information

Authors and Affiliations

  1. Boehringer Ingelheim Pharma GMBH & CO. KG, Biberach an der Riss, Germany

    Stefan Schlatter, Michael Dieterle & Hitto Kaufmann

  2. Boehringer Ingelheim Pharma GmbH & Co. KG, BP Process Science, Birkendorfer Straße 65, D-88397, Biberach an der Riss, Germany

    Hitto Kaufmann

Authors
  1. Stefan Schlatter
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  2. Michael Dieterle
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  3. Hitto Kaufmann
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Corresponding author

Correspondence to Hitto Kaufmann.

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Schlatter, S., Dieterle, M. & Kaufmann, H. Einwegsysteme in zellkulturbasierten Herstellprozessen für Biopharmazeutika. Biospektrum 18, 442–443 (2012). https://doi.org/10.1007/s12268-012-0204-x

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  • DOI: https://doi.org/10.1007/s12268-012-0204-x

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