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Intelligente Wachstumsmedien mit kontrollierter Substratfreisetzung

Bioprozessentwicklung

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Abstract

Intelligent growth media with a biocatalytically controlled substrate release from soluble polymers allow controlled growth and higher productivities. They are also a valuable tool for consistent bioprocess development through the different scales, because they guarantee similar growth conditions from the initial screening stage in 96-microwell plates and shake flasks to the final fed-batch bioprocess in a bioreactor.

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Correspondence to Peter Neubauer.

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Peter Neubauer Jahrgang 1962. Mikrobiologiestudium an der Universität Greifswald. 1992 Promotion. 1993–1995 Postdoc am Royal Institute of Technology KTH, Stockholm, Schweden. 1995–2000 wissenschaftlicher Mitarbeiter und Leiter der AG Fermentation an der Universität Halle-Wittenberg. 2000–2008 Professor für Bioprocess Engineering an der Universität Oulu, Finnland. 2006 Stipendiat der Alfried Krupp von Bohlen und Halbach-Stiftung. Seit 2008 Lehrstuhl für Bioverfahrenstechnik an der TU Berlin.

Stefan Junne Jahrgang 1977. Studium des Chemieingenieurwesens an der Universität Erlangen-Nürnberg. 2010 Promotion an der TU Berlin. Wissenschaftlicher Mitarbeiter am Fachgebiet Bioverfahrenstechnik, Institut für Biotechnologie, TU Berlin, Leitung der Arbeiten im Bereich Bioprozesstechnik und Modellierung.

Juozas Šiurkus Jahrgang 1980. Chemical Engineering-Studium an der Kaunas University of Technology, Litauen. Master in Biotechnology Sciences, Technical University of Denmark, Kopenhagen. 2004–2011 Wissenschaftler bei Fermentas UAB; seit 2011 R&D Manager bei Thermo Fisher Scientific (ehemals Fermentas), Vilnius, Litauen. Seit 2007 Promotionsstudent bei Prof. Dr. Neubauer, erst Universität Oulu, Finnland, dann TU Berlin.

Julia Glazyrina Jahrgang 1978. Biotechnologiestudium an der Technischen Universität Kazan, Russland. Seit 2009 wissenschaftliche Mitarbeiterin/Doktorandin am Fachgebiet Bioverfahrenstechnik, Institut für Biotechnologie, TU Berlin.

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Neubauer, P., Šiurkus, J., Junne, S. et al. Intelligente Wachstumsmedien mit kontrollierter Substratfreisetzung. Biospektrum 18, 162–164 (2012). https://doi.org/10.1007/s12268-012-0159-y

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  • DOI: https://doi.org/10.1007/s12268-012-0159-y

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