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Bestimmung der Inhibition der mitochondrialen Biogenese

  • Anwendungen & Produkte
  • In-Cell-ELISA
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BIOspektrum Aims and scope

Abstract

Mitochondria are produced from the transcription and translation of genes both in the nuclear genome and in the mitochondrial genome, termed mitobiogenesis. Measuring mitobiogenesis is useful for early toxicity screening of new drug candidates. This requires an assay that is quantitative, specific, and reproducible and is also flexible enough to be applied in a variety of cell types.

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Literatur

  1. Food and Drug Administration (2006) Guidance for Industry; Antiviral Product Development — Conducting and Submitting Virology Studies to the Agency. www.fda.gov/OHRMS/DOCKETS/98fr/05d-0183-gdl0002-01.pdf

  2. Food and Drug Administration (2009) Guidance for Industry; Drug-Induced Liver Injury: Premarketing Clinical Evaluation. www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM174090.pdf

  3. Medeiros, DM (2008) Assessing mitochondria biogenesis. Methods 46:288–294

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Author information

Authors and Affiliations

  1. Abcam Plc, Cambridge, UK

    James Murray, Daniel Schwartz & Jan Hryca

  2. Abcam plc, 330 Cambridge Science Park, Cambridge, UK, CB4 0FL

    James Murray, Daniel Schwartz & Jan Hryca

Authors
  1. James Murray
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  2. Daniel Schwartz
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  3. Jan Hryca
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Corresponding author

Correspondence to James Murray.

Additional information

James Murray, Daniel Schwartz und Jan Hryca (v. l. n. r.)

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Murray, J., Schwartz, D. & Hryca, J. Bestimmung der Inhibition der mitochondrialen Biogenese. Biospektrum 18, 60–61 (2012). https://doi.org/10.1007/s12268-012-0145-4

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  • DOI: https://doi.org/10.1007/s12268-012-0145-4

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