BIOspektrum

, Volume 17, Issue 4, pp 393–395 | Cite as

Abwehr gegen Fremd-DNA durch das bakterielle CRISPR/Cas-System

Wissenschaft Mikrobielles „Immunsystem“
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Zusammenfassung

Kurze Fremd-DNA-Sequenzen werden in bakterielle Genome integriert (CRISPR-Arrays) und dienen nach Transkription und Prozessierung zusammen mit einem Set konservierter Proteine (Cas-Proteine) zur Identifikation und Elimination von eingedrungener DNA.

Abstract

Short foreign DNA sequences are integrated in bacterial genomes (CRISPR arrays), where they operate after transcription and processing together with a set of conserved proteins (Cas proteins) to target and destroy DNA that had invaded the cell.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  1. 1.Molekularbiologie der BakterienUniversität DüsseldorfDüsseldorfGermany
  2. 2.Institut für Physikalische Biologie Molekularbiologie der BakterienHeinrich-Heine-Universität DüsseldorfDüsseldorfGermany

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