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Die CTD der RNA-Polymerase II — eine neue Ebene der Genregulation

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Zusammenfassung

Die C-terminale Domäne (CTD) der RNA-Polymerase II (RNAPII) ermöglicht die Transkription von Chromatin, koordiniert viele RNA-Reifungsschritte und ist wichtig für das Lesen und Schreiben epigenetischer Information.

Abstract

The carboxy-terminal domain (CTD) of RNA polymerase II (RNAPII) facilitates transcription of chromatin, coordinates diverse RNA maturation steps, and is important for reading and writing of epigenetic information.

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Authors and Affiliations

  1. Abteilung Molekulare Epigenetik, Helmholtz-Zentrum München, München, Germany

    Martin Heidemann, Corinna Hintermair, Roland Schüller, Kirsten Voss & Dirk Eick

  2. Abteilung für Molekulare Epigenetik, Helmholtz-Zentrum München, Marchioninistraße 25, D-81377, München, Germany

    Dirk Eick

Authors
  1. Martin Heidemann
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  2. Corinna Hintermair
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  3. Roland Schüller
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  4. Kirsten Voss
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  5. Dirk Eick
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Corresponding author

Correspondence to Dirk Eick.

Additional information

Kirsten Vo Corinna Hintermair und Roland Schüller (v. l. n. r.)

Die Autoren arbeiten gemeinsam in der Abteilung für Molekulare Epigenetik des Helmholtz-Zentrums München. Hauptziel ihrer Forschung ist die Aufklärung der molekularen Wirkungsweise der RNAPIICTD und wie Fehlfunktionen der CTD zur Entstehung von Krankheiten beitragen.

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Heidemann, M., Hintermair, C., Schüller, R. et al. Die CTD der RNA-Polymerase II — eine neue Ebene der Genregulation. Biospektrum 17, 270–273 (2011). https://doi.org/10.1007/s12268-011-0040-4

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  • DOI: https://doi.org/10.1007/s12268-011-0040-4

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