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Die Funktion des PAR/aPKC-Komplexes in Drosophila

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  • Zellpolarität
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BIOspektrum Aims and scope

Zusammenfassung

Viele Zelltypen in mehrzelligen Organismen weisen eine ausgeprägte Polarität auf, die für die Funktion der Zellen von größter Bedeutung ist. Die Kontrolle der Zellpolarität erfolgt durch ein evolutionär hochkonserviertes Netzwerk interagierender Proteine.

Abstract

Many cell types in multicellular organisms possess a pronounced polarity that is of great importance for the function of the cells. Cell polarity is controlled by an evolutionarily conserved network of interacting proteins.

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Authors and Affiliations

  1. Abteilung Stammzellbiologie, DFG Forschungszentrum für Molekularphysiologie des Gehirns (CMPB), Universität Göttingen, Göttingen, Germany

    Michael P. Krahn, Soya Kim, Ieva Gailite, Nils Halbsgut & Andreas Wodarz

  2. Institut für Genetik, Universität Düsseldorf, Düsseldorf, Germany

    Soya Kim

  3. DFG-Forschungszentrum für Molekularphysiologie des Gehirns (CMPB), Georg-August-Universität Göttingen, Justus-von-Liebig-Weg 11, D-37077, Göttingen, Germany

    Andreas Wodarz

Authors
  1. Michael P. Krahn
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  2. Soya Kim
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  3. Ieva Gailite
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  4. Nils Halbsgut
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  5. Andreas Wodarz
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Corresponding author

Correspondence to Andreas Wodarz.

Additional information

Die Arbeitsgruppe von Andreas Wodarz befasst sich mit verschiedenen Aspekten der Zellpolarität. Insbesondere ist sie an den molekularen Mechanismen interessiert, die die Etablierung und Aufrechterhaltung der apiko-basalen Zellpolarität in Epithelien und neuralen Vorläuferzellen der Taufliege Drosophila steuern.

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Krahn, M.P., Kim, S., Gailite, I. et al. Die Funktion des PAR/aPKC-Komplexes in Drosophila . Biospektrum 17, 154–156 (2011). https://doi.org/10.1007/s12268-011-0020-8

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  • DOI: https://doi.org/10.1007/s12268-011-0020-8

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