Skip to main content
Log in

Translating Trial Results in Clinical Practice: the Risk GP Model

  • Commentary
  • Published:
Journal of Cardiovascular Translational Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abbreviations

AR:

Absolute risk

ARR:

Absolute risk reduction

CVD:

Cardiovascular disease

KT:

Knowledge translation

Risk GP:

Risk generalization-particularization

References

  1. Woolf, S. H. (2008). The meaning of translational research and why it matters. JAMA, 299(2), 211–213.

    Article  CAS  PubMed  Google Scholar 

  2. Fixsen, D. L., Naoom, S. F., Blase, K. A., Friedman, R. M., & Wallace, F. (2005). Implementation research: a synthesis of the literature. Tampa: National Implementation Research Network, University of South Florida.

    Google Scholar 

  3. Fuller, J., & Flores, L. J. (2015). The risk GP model: the standard model of prediction in medicine. Studies in History and Philosophy of Biological and Biomedical Sciences, 54, 49–61.

    Article  PubMed  Google Scholar 

  4. Baigent, C., Keech, A., Kearney, P. M., Blackwell, L., Buck, G., Pollicino, C., et al. (2005). Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet, 366(9493), 1267–1278.

    Article  CAS  PubMed  Google Scholar 

  5. Dawid, P. (2015). On individual risk. Synthese. doi:10.1007/s11229-015-0953-4.

    Google Scholar 

Download references

Acknowledgments

JF gratefully acknowledges funding support from the Canadian Institutes of Health Research. LJF is thankful for funding from the Chilean National Commission for Scientific and Technological Research (CONYCIT).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jonathan Fuller.

Ethics declarations

No human studies and no animal studies were carried out by the authors for this article.

Conflict of Interest

The authors declare that they have no conflict of interest.

Sources of Funding

Canadian Institutes of Health Research and Chilean National Commission for Scientific and Technological Research (CONYCIT).

Additional information

Associate Editor Craig Stolen oversaw the review of this article

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fuller, J., Flores, L.J. Translating Trial Results in Clinical Practice: the Risk GP Model. J. of Cardiovasc. Trans. Res. 9, 167–168 (2016). https://doi.org/10.1007/s12265-016-9694-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12265-016-9694-0

Keywords

Navigation