Abstract
We sought to examine the efficacy in preventing surgical site infection (SSI) in cardiac surgery, using two different incise drapes (not iodine-impregnated and iodine-impregnated). A cost analysis was also considered. Between January 2008 and March 2015, 5100 consecutive cardiac surgery patients, who underwent surgery in our Institute, were prospectively collected. A total of 3320 patients received a standard not iodine-impregnated steri-drape (group A), and 1780 patients received Ioban® 2 drape (group B). We investigated, by a propensity matched analysis, whether the use of standard incise drape or iodine-impregnated drape would impact upon SSI rate. Totally, 808 patients for each group were matched for the available risk factors. Overall incidence of SSI was significantly higher in group A (6.5 versus 1.9 %) (p = 0.001). Superficial SSI incidence was significantly higher in group A (5.1 vs 1.6 %) (p = 0.002). Deep SSI resulted higher in group A (1.4 %) than in group B (0.4 %), although not significantly (p = 0.11). Consequently, the need for vacuum-assisted closure (VAC) therapy use resulted 4.3 % in group A versus 1.2 % in group B (p = 0.001). Overall costs for groups A and B were 12.494.912 € and 11.721.417 €, respectively. The Ioban® 2 offered totally 773.495 € cost savings compared to standard steri-drape. Ioban 2 drape assured a significantly lower incidence of SSI. Additionally, Ioban® 2 drape proved to be cost-effective in cardiac surgery.
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The corresponding author accepts responsibility for the integrity of the submitted work. The authors declare as follows: we do not have a commercial or other association that might pose a conflict of interest, we do not have sources of financial support. Jonida Bejko declares that she has no conflict of interest. Vincenzo Tarzia declares that he has no conflict of interest. Massimiliano Carrozzini declares that he has no conflict of interest. Michele Gallo declares that he has no conflict of interest. Giacomo Bortolussi declares that he has no conflict of interest. Marina Comisso declares that she has no conflict of interest. Luca Testolin declares that he has no conflict of interest. Cosimo Guglielmi declares that he has no conflict of interest. Marco De Franceschi declares that he has no conflict of interest. Roberto Bianco declares that he has no conflict of interest. Gino Gerosa declares that he has no conflict of interest. Tomaso Bottio declares that he has no conflict of interest.
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This article does not contain any studies with animals performed by any of the authors.
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Informed consent was obtained from all individual participants included in the study.
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Associate Editor Emanuele Barbato oversaw the review of this article
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Bejko, J., Tarzia, V., Carrozzini, M. et al. Comparison of Efficacy and Cost of Iodine Impregnated Drape vs. Standard Drape in Cardiac Surgery: Study in 5100 Patients. J. of Cardiovasc. Trans. Res. 8, 431–437 (2015). https://doi.org/10.1007/s12265-015-9653-1
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DOI: https://doi.org/10.1007/s12265-015-9653-1