References
Liu Y, Sun Y, Zhao X, Kim JY, Luo L, Wang Q. Enhancement of aggression induced by isolation rearing is associated with a lack of central serotonin. Neurosci Bull 2019, 35: 841–852.
Premoli M, Pietropaolo S, Wöhr M, Simola N, Bonini SA. Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications. Eur J Neurosci 2023, 57: 2062–2096.
Nemsadze K, Silagava M. Neuroendocrine foundation of maternal-child attachment. Georgian Med News 2010: 21–26.
Mosienko V, Beis D, Alenina N, Wöhr M. Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin. Mol Autism 2015, 6: 13.
Liu Y, Shan L, Liu T, Li J, Chen Y, Sun C, et al. Molecular and cellular mechanisms of the first social relationship: A conserved role of 5-HT from mice to monkeys, upstream of oxytocin. Neuron 2023, 111: 1468-1485.e7.
Walther DJ, Peter JU, Bashammakh S, Hörtnagl H, Voits M, Fink H, et al. Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 2003, 299: 76.
Beis D, Holzwarth K, Flinders M, Bader M, Wöhr M, Alenina N. Brain serotonin deficiency leads to social communication deficits in mice. Biol Lett 2015, 11: 20150057.
Kraemer GW. Psychobiology of early social attachment in Rhesus monkeys clinical implications. Ann NY Acad Sci 1997, 807: 401–418.
Winslow JT, Hearn EF, Ferguson J, Young LJ, Matzuk MM, Insel TR. Infant vocalization, adult aggression, and fear behavior of an oxytocin null mutant mouse. Horm Behav 2000, 37: 145–155.
Yang G, Geng H, Hu C. Targeting 5-HT as a potential treatment for social deficits in autism. Neurosci Bull 2022, 38: 1263–1266.
Acknowledgements
This highlight was supported by the National Natural Science Foundation of China (32125018 and 32071005), the National Key Research and Development Program of China (2021YFA1101701), the Fundamental Research Funds for the Central Universities, the MOE Frontiers Science Center for Brain Science & Brain-Machine Integration of Zhejiang University, and Innovative Research Team of High-level Local Universities in Shanghai (SHSMU–ZDCX20211102).
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Fan, J., Xu, H. Serotonin: A Bridge for Infant-mother Bonding. Neurosci. Bull. 39, 1741–1744 (2023). https://doi.org/10.1007/s12264-023-01117-7
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DOI: https://doi.org/10.1007/s12264-023-01117-7