Skip to main content
Log in

Rapid Eye Movement Sleep Consolidates Social Memory

  • Research Highlight
  • Published:
Neuroscience Bulletin Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Dang R, Zhou Y, Zhang Y, Liu D, Wu M, Liu A. Regulation of social memory by lateral entorhinal cortical projection to dorsal hippocampal CA2. Neurosci Bull 2022, 38: 318–322.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Girardeau G, Lopes-Dos-Santos V. Brain neural patterns and the memory function of sleep. Science 2021, 374: 560–564.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Chen S, He L, Huang AJY, Boehringer R, Robert V, Wintzer ME, et al. A hypothalamic novelty signal modulates hippocampal memory. Nature 2020, 586: 270–274.

    Article  CAS  PubMed  Google Scholar 

  4. Renouard L, Billwiller F, Ogawa K, Clément O, Camargo N, Abdelkarim M, et al. The supramammillary nucleus and the claustrum activate the cortex during REM sleep. Sci Adv 2015, 1: e1400177.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Qin H, Fu L, Jian T, Jin W, Liang M, Li J, et al. REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation. Neuron 2022, 110: 4000-4014.e6.

    Article  CAS  PubMed  Google Scholar 

  6. Aguggia JP, Cornejo MP, Fernandez G, De Francesco PN, Mani BK, Cassano D, et al. Growth hormone secretagogue receptor signaling in the supramammillary nucleus targets nitric oxide-producing neurons and controls recognition memory in mice. Psychoneuroendocrinology 2022, 139: 105716.

    Article  CAS  PubMed  Google Scholar 

  7. Li W, Ma L, Yang G, Gan WB. REM sleep selectively prunes and maintains new synapses in development and learning. Nat Neurosci 2017, 20: 427–437.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Banker SM, Gu X, Schiller D, Foss-Feig JH. Hippocampal contributions to social and cognitive deficits in autism spectrum disorder. Trends Neurosci 2021, 44: 793–807.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Porcelli S, Van Der Wee N, van der Werff S, Aghajani M, Glennon JC, van Heukelum S, et al. Social brain, social dysfunction and social withdrawal. Neurosci Biobehav Rev 2019, 97: 10–33.

    Article  PubMed  Google Scholar 

  10. Cope EC, Zych AD, Katchur NJ, Waters RC, Laham BJ, Diethorn EJ, et al. Atypical perineuronal nets in the CA2 region interfere with social memory in a mouse model of social dysfunction. Mol Psychiatry 2022, 27: 3520–3531.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This highlight was supported by the National Natural Science Foundation of China (32125018 and 32071005), the Fundamental Research Funds for the Central Universities, the MOE Frontiers Science Center for Brain Science & Brain-Machine Integration of Zhejiang University, and the Innovative Research Team of High-level Local Universities in Shanghai (SHSMU-ZDCX20211102).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Han Xu.

Ethics declarations

Conflict of interest

The author declares no competing interest.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fan, J., Zhou, F., Zheng, J. et al. Rapid Eye Movement Sleep Consolidates Social Memory. Neurosci. Bull. 39, 1598–1600 (2023). https://doi.org/10.1007/s12264-023-01080-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12264-023-01080-3

Navigation