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The Objective Assessment of Event-Related Potentials: An Influence of Chronic Pain on ERP Parameters

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Abstract

The article presents an original method for the automatic assessment of the quality of event-related potentials (ERPs), based on the calculation of the coefficient ε, which describes the compliance of recorded ERPs with some statistically significant parameters. This method was used to analyze the neuropsychological EEG monitoring of patients suffering from migraines. The frequency of migraine attacks was correlated with the spatial distribution of the coefficients ε, calculated for EEG channels. More than 15 migraine attacks per month was accompanied by an increase in calculated values in the occipital region. Patients with infrequent migraines exhibited maximum quality in the frontal areas. The automatic analysis of spatial maps of the coefficient ε demonstrated a statistically significant difference between the two analyzed groups with different means of migraine attack numbers per month.

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Acknowledgments

This work was partially supported by the Russian Federation Government Grant No. 075-15-2022-1094 (clinical data processing). Another part of this work (developing the numeric method of data processing) was supported by the Ministry of Science and Higher Education of the Russian Federation in the framework of the state assignment (FSRR-2020-0003). The clinical experimental work was partially supported by the Russian Foundation for Basic Research (20-02-00752).

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Author notes

  1. Maksim Zhuravlev, Anton Selskii, and Anastasiya Runnova contributed equally to this work.

Authors and Affiliations

  1. Coordinating Center for Fundamental Research, National Medical Research Center for Therapy and Preventive Medicine, Moscow, 101000, Russia

    Maksim Zhuravlev & Anastasiya Runnova

  2. Institute of Physics, Saratov State University, Saratov, 410012, Russia

    Maksim Zhuravlev & Anton Selskii

  3. Department of Fundamental Research in Neurocardiology, Institute of Cardiological Research, Saratov State Medical University, Saratov, 410012, Russia

    Mikhail Novikov, Ruzanna Parsamyan, Anton Selskii & Anastasiya Runnova

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  1. Maksim Zhuravlev
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Correspondence to Maksim Zhuravlev.

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Zhuravlev, M., Novikov, M., Parsamyan, R. et al. The Objective Assessment of Event-Related Potentials: An Influence of Chronic Pain on ERP Parameters. Neurosci. Bull. 39, 1105–1116 (2023). https://doi.org/10.1007/s12264-023-01035-8

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