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Drosophila Larval Light-Avoidance is Negatively Regulated by Temperature Through Two Pairs of Central Brain Neurons

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References

  1. 1.

    Jeong YT, Oh SM, Shim J, Seo JT, Kwon JY, Moon SJ. Mechanosensory neurons control sweet sensing in Drosophila. Nat Commun 2016, 7: 12872.

    Article  Google Scholar 

  2. 2.

    Head LM, Tang X, Hayley SE, Goda T, Umezaki Y, Chang EC. The influence of light on temperature preference in Drosophila. Curr Biol 2015, 25: 1063–1068.

    CAS  Article  Google Scholar 

  3. 3.

    Keene AC, Mazzoni EO, Zhen J, Younger MA, Yamaguchi S, Blau J, et al. Distinct visual pathways mediate Drosophila larval light avoidance and circadian clock entrainment. J Neurosci 2011, 31: 6527–6534.

    CAS  Article  Google Scholar 

  4. 4.

    Keene AC, Sprecher SG. Seeing the light: photobehavior in fruit fly larvae. Trends Neurosci 2012, 35: 104–110.

    CAS  Article  Google Scholar 

  5. 5.

    Larderet I, Fritsch PM, Gendre N, Neagu-Maier GL, Fetter RD, Schneider-Mizell CM, et al. Organization of the Drosophila larval visual circuit. Elife 2017, 6: e28387.

    Article  Google Scholar 

  6. 6.

    Humberg TH, Bruegger P, Afonso B, Zlatic M, Truman JW, Gershow M, et al. Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues. Nat Commun 2018, 9: 1260.

    Article  Google Scholar 

  7. 7.

    Gong Z, Liu J, Guo C, Zhou Y, Teng Y, Liu L. Two pairs of neurons in the central brain control Drosophila innate light preference. Science 2010, 330: 499–502.

    CAS  Article  Google Scholar 

  8. 8.

    Gong C, Ouyang Z, Zhao W, Wang J, Li K, Zhou P, et al. A neuronal pathway that commands deceleration in Drosophila larval light-avoidance. Neurosci Bull 2019, 35: 959–968.

    CAS  Article  Google Scholar 

  9. 9.

    Zhao W, Zhou P, Gong C, Ouyang Z, Wang J, Zheng N, et al. A disinhibitory mechanism biases Drosophila innate light preference. Nat Commun 2019, 10: 124.

    Article  Google Scholar 

  10. 10.

    Isaacman-Beck J, Paik KC, Wienecke CFR, Yang HH, Fisher YE, Wang IE, et al. SPARC enables genetic manipulation of precise proportions of cells. Nat Neurosci 2020, 23: 1168–1175.

    CAS  Article  Google Scholar 

  11. 11.

    Luo JJ, Shen WL, Montell C. TRPA1 mediates sensation of the rate of temperature change in Drosophila larvae. Nat Neurosci 2017, 20: 34–41.

    CAS  Article  Google Scholar 

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Acknowledgements

We thank Jiangqu Liu for constructive discussions and Yufeng Pan and Fang Guo for sharing fly strains. We acknowledge the Bloomington Drosophila stock center and Qinghua Drosophila Stock center for providing the fly stocks and the core facilities of Zhejiang University School of Medicine for technical support and reagents. This work was supported by Zhejiang Lab (2020KB0AC02), the National Natural Science Foundation of China (31070944, 31271147, 31471063, 31671074, and 61572433) and the Fundamental Research Funds for the Central Universities, China (2017FZA7003).

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Correspondence to Zhefeng Gong.

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Wang, J., Zhao, W., Zhao, Q. et al. Drosophila Larval Light-Avoidance is Negatively Regulated by Temperature Through Two Pairs of Central Brain Neurons. Neurosci. Bull. (2021). https://doi.org/10.1007/s12264-021-00785-7

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