Synaptic Adaptation Contributes to Stimulus-Specific Adaptation in the Thalamic Reticular Nucleus

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  1. 1.

    Parras GG, Nieto-Diego J, Carbajal GV, Valdes-Baizabal C, Escera C, Malmierca MS. Neurons along the auditory pathway exhibit a hierarchical organization of prediction error. Nat Commun 2017, 8: 2148.

    Article  Google Scholar 

  2. 2.

    Malmierca MS, Sanchez-Vives MV, Escera C, Bendixen A. Neuronal adaptation, novelty detection and regularity encoding in audition. Front Syst Neurosci 2014, 8: 111.

    PubMed  PubMed Central  Google Scholar 

  3. 3.

    Vinken K, Vogels R, Op de Beeck H. Recent visual experience shapes visual processing in rats through stimulus-specific adaptation and response enhancement. Curr Biol 2017, 27: 914–919.

  4. 4.

    Mill R, Coath M, Wennekers T, Denham SL. A neurocomputational model of stimulus-specific adaptation to oddball and markov sequences. PLoS Comput Biol 2011, 7.

  5. 5.

    Shen L, Zhao L, Hong B. Frequency-specific adaptation and its underlying circuit model in the auditory midbrain. Front Neural Circuits 2015, 9: 55.

    Article  Google Scholar 

  6. 6.

    Pinault D. The thalamic reticular nucleus: structure, function and concept. Brain Res Rev 2004, 46: 1–31.

    Article  Google Scholar 

  7. 7.

    Zhai YY, Sun ZH, Gong YM, Tang Y, Yu X. Integrative stimulus-specific adaptation of the natural sounds in the auditory cortex of the awake rat. Brain Struct Funct 2019, 224: 1753–1766.

    Article  Google Scholar 

  8. 8.

    Rui YY, He J, Zhai YY, Sun ZH, Yu X. Frequency-dependent stimulus-specific adaptation and regularity sensitivity in the rat auditory thalamus. Neuroscience 2018, 392: 13–24.

    CAS  Article  Google Scholar 

  9. 9.

    Jones EG. The Thalamus. 2nd ed. Cambridge; New York: Cambridge University Press, 2007.

    Google Scholar 

  10. 10.

    Golshani P, Liu XB, Jones EG. Differences in quantal amplitude reflect GluR4- subunit number at corticothalamic synapses on two populations of thalamic neurons. Proc Natl Acad Sci U S A 2001, 98: 4172–4177.

    CAS  Article  Google Scholar 

  11. 11.

    Yu XJ, Meng XK, Xu XX, He J. Individual auditory thalamic reticular neurons have large and cross-modal sources of cortical and thalamic inputs. Neuroscience 2011, 193: 122–131.

    CAS  Article  Google Scholar 

  12. 12.

    Wang H, Han YF, Chan YS, He J. Stimulus-specific adaptation at the synapse level in vitro. PLoS One 2014, 9: e114537.

    Article  Google Scholar 

  13. 13.

    Natan RG, Briguglio JJ, Mwilambwe-Tshilobo L, Jones SI, Aizenberg M, Goldberg EM, et al. Complementary control of sensory adaptation by two types of cortical interneurons. Elife 2015, 4.

  14. 14.

    Nieto-Diego J, Malmierca MS. Topographic distribution of stimulus-specific adaptation across auditory cortical fields in the anesthetized rat. PLoS Biol 2016, 14: e1002397.

    Article  Google Scholar 

  15. 15.

    Chen Z, Parkkonen L, Wei J, Dong JR, Ma Y, Carlson S. Prepulse inhibition of auditory cortical responses in the caudolateral superior temporal gyrus in Macaca mulatta. Neurosci Bull 2018, 34: 291–302.

    CAS  Article  Google Scholar 

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This work was supported by the National Natural Science Foundation of China (31671081 and 31872768).

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Correspondence to Xiongjie Yu.

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Zhai, YY., Auksztulewicz, R., Song, PR. et al. Synaptic Adaptation Contributes to Stimulus-Specific Adaptation in the Thalamic Reticular Nucleus. Neurosci. Bull. 36, 1538–1541 (2020).

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