This is a preview of subscription content, access via your institution.
Buy single article
Instant access to the full article PDF.
Tax calculation will be finalised during checkout.
de Waal FBM, Preston SD. Mammalian empathy: behavioural manifestations and neural basis. Nat Rev Neurosci 2017, 18: 498–509.
Chen J. Empathy for distress in humans and rodents. Neurosci Bull 2018, 34: 216–236.
Langford DJ, Crager SE, Shehzad Z, Smith SB, Sotocinal SG, Levenstadt JS, et al. Social modulation of pain as evidence for empathy in mice. Science 2006, 312: 1967–1970.
Du R, Luo WJ, Geng KW, Li CL, Yu Y, Wei N, et al. Empathic contagious pain and consolation in laboratory rodents: species and sex comparisons. Neurosci Bull 2020. https://doi.org/10.1007/s12264-020-00465-y.
Li CL, Yu Y, He T, Wang RR, Geng KW, Du R, et al. Validating rat model of empathy for pain: effects of pain expressions in social partners. Front Behav Neurosci 2018, 12: 242.
Yu YQ, Barry DM, Hao Y, Liu XT, Chen ZF. Molecular and neural basis of contagious itch behavior in mice. Science 2017, 355: 1072–1076.
Burkett JP, Andari E, Johnson ZV, Curry DC, de Waal FBM, Young LJ. Oxytocin-dependent consolation behavior in rodents. Science 2016, 351: 375–378.
Lamm C, Decety J, Singer T. Meta-analytic evidence for common and distinct neural networks associated with directly experienced pain and empathy for pain. Neuroimage 2011, 54: 2492–2502.
Smith ML, Hostetler CM, Heinricher MM, Ryabinin AE. Social transfer of pain in mice. Sci Adv 2016, 2: e1600855.
Grimes WN, Songco-Aguas A, Rieke F. Parallel processing of rod and cone signals: retinal function and human perception. Annu Rev Vis Sci 2018, 4: 123–141.
Spitschan M, Lucas RJ, Brown TM. Chromatic clocks: color opponency in non-image-forming visual functions. Neurosci Biobehav Rev 2017, 78: 24–33.
Allen AE, Storchi R, Martial FP, Bedford RA, Lucas RJ. Melanopsin contributions to the representation of images in the early visual system. Curr Biol 2017, 27: 1623–1632.e4.
Sonoda T, Lee SK, Birnbaumer L, Schmidt TM. Melanopsin phototransduction is repurposed by ipRGC subtypes to shape the function of distinct visual circuits. Neuron 2018, 99: 754–767.e4.
Glickfeld LL, Olsen SR. Higher-order areas of the mouse visual cortex. Annu Rev Vis Sci 2017, 3: 251–273.
Carrillo M, Han YY, Migliorati F, Liu M, Gazzola V, Keysers C. Emotional mirror neurons in the rat’s anterior cingulate cortex. Curr Biol 2019, 29: 1301–1312.e6.
We are grateful to YQ Yu, YJ Yin, Y Yang, and F Yang for cooperation and XL Wang for animal support. This work was supported by grants from the National Natural Science Foundation of China (81571072 and 31600855) and the Military Laboratory Animal Project (SYDW14 and SYDW07).
Conflict of interest
The authors have no conflicts of interest to declare.
Electronic Supplementary Material
Below is the link to the electronic supplementary material.
About this article
Cite this article
Geng, KW., Du, R., Wei, N. et al. Image-Forming Visual Basis of Empathy for Pain in Mice. Neurosci. Bull. 36, 1563–1569 (2020). https://doi.org/10.1007/s12264-020-00528-0