Towards the Framework of Understanding Autism Spectrum Disorders

This is a preview of subscription content, log in to check access.


  1. 1.

    Iakoucheva LM, Muotri AR, Sebat J. Getting to the cores of autism. Cell 2019, 178: 1287–1298.

    CAS  Article  Google Scholar 

  2. 2.

    Zhou B, Zhou H, Wu L, Zou X, Luo X, Fombonne E, et al. Assessing the accuracy of the modified chinese autism spectrum rating scale and social responsiveness scale for screening autism spectrum disorder in Chinese children. Neurosci Bull 2017, 33: 168–174.

    Article  Google Scholar 

  3. 3.

    Wang S, Deng H, You C, Chen K, Li J, Tang C, et al. Sex differences in diagnosis and clinical phenotypes of Chinese children with autism spectrum disorder. Neurosci Bull 2017, 33: 153–160.

    Article  Google Scholar 

  4. 4.

    Lainhart JE. Brain imaging research in autism spectrum disorders: in search of neuropathology and health across the lifespan. Curr Opin Psychiatry 2015, 28: 76–82.

    Article  Google Scholar 

  5. 5.

    Shou XJ, Xu XJ, Zeng XZ, Liu Y, Yuan HS, Xing Y, et al. A volumetric and functional connectivity MRI study of brain arginine-vasopressin pathways in autistic children. Neurosci Bull 2017, 33: 130–142.

    CAS  Article  Google Scholar 

  6. 6.

    Li Y, Fang H, Zheng W, Qian L, Xiao Y, Wu Q, et al. A fiber tractography study of social-emotional related fiber tracts in children and adolescents with autism spectrum disorder. Neurosci Bull 2017, 33: 722–730.

    Article  Google Scholar 

  7. 7.

    Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, et al. Synaptic and gene regulatory mechanisms in schizophrenia, autism, and 22q11.2 copy number variant-mediated risk for neuropsychiatric disorders. Biol Psychiatry 2019.

    Article  PubMed  Google Scholar 

  8. 8.

    Xu M, Ji Y, Zhang T, Jiang X, Fan Y, Geng J, et al. Clinical application of chromosome microarray analysis in Han Chinese children with neurodevelopmental disorders. Neurosci Bull 2018, 34: 981–991.

    CAS  Article  Google Scholar 

  9. 9.

    Qian A, Wang X, Liu H, Tao J, Zhou J, Ye Q, et al. Dopamine D4 receptor gene associated with the frontal-striatal-cerebellar loop in children with ADHD: A resting-state fMRI study. Neurosci Bull 2018, 34: 497–506.

    CAS  Article  Google Scholar 

  10. 10.

    Tian Y, Zhang ZC, Han J. Drosophila studies on autism spectrum disorders. Neurosci Bull 2017, 33: 737–746.

    Article  Google Scholar 

  11. 11.

    Liu Z, Li X, Zhang JT, Cai YJ, Cheng TL, Cheng C, et al. Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature 2016, 530: 98–102.

    CAS  Article  Google Scholar 

  12. 12.

    Liu H, Chen Y, Niu Y, Zhang K, Kang Y, Ge W, et al. TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys. Cell Stem Cell 2014, 14: 323–328.

    CAS  Article  Google Scholar 

  13. 13.

    Chen Y, Yu J, Niu Y, Qin D, Liu H, Li G, et al. Modeling rett syndrome using TALEN-edited MECP2 mutant cynomolgus monkeys. Cell 2017, 169: 945–955 e910.

    Google Scholar 

  14. 14.

    Zhao H, Tu Z, Xu H, Yan S, Yan H, Zheng Y, et al. Altered neurogenesis and disrupted expression of synaptic proteins in prefrontal cortex of SHANK3-deficient non-human primate. Cell Res 2017, 27: 1293–1297.

    CAS  Article  Google Scholar 

  15. 15.

    Tu Z, Zhao H, Li B, Yan S, Wang L, Tang Y, et al. CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms. Hum Mol Genet 2019, 28: 561–571.

    CAS  Article  Google Scholar 

  16. 16.

    Zhou Y, Sharma J, Ke Q, Landman R, Yuan J, Chen H, et al. Atypical behaviour and connectivity in SHANK3-mutant macaques. Nature 2019, 570: 326–331.

    CAS  Article  Google Scholar 

Download references

Author information



Corresponding author

Correspondence to Zilong Qiu.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Qiu, Z., Yuan, B. Towards the Framework of Understanding Autism Spectrum Disorders. Neurosci. Bull. 35, 1110–1112 (2019).

Download citation