Perspective on Etiology and Treatment of Bipolar Disorders in China: Clinical Implications and Future Directions
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Bipolar disorder (BD) is a chronic, recurrent, disabling disease, even when given currently-available pharmacological and psychological treatments. Currently, the etiology and pathogenesis of BD remain unclear. As a consequence, patients with BD are frequently unrecognized, misdiagnosed, and inappropriately treated, which often yields a low treatment response and poor outcome. In the last decade or so, researchers in the fields of neuroscience and clinical psychiatry in China have worked together to explore the clinical phenomenology, etiology and pathogenesis of BD, and to investigate strategies for the treatment and management of BD. These efforts have not only moved researches in BD forward, but also have changed the practice of treating BD in China.
Etiology and Pathogenesis of BD
This insight article was supported by the National Key Research and Development Program of China (2016YFC1307100 and 2016YFC1307105), the Shanghai Key Medicine Specialties Program (ZK2015A06), Projects of International Cooperation and Exchanges National Natural Science Foundation of China (81761128032), and the Sanming Project of Medicine in Shenzhen, China (SZSM201612006).
Conflict of interest
The authors claim that there are no conflicts of interest.
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