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Omentum Rotational Flap for Spleen Autotransplantation in Splenic Trauma — Experimental Study

  • Surgical Techniques and Innovations
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Abstract

Intra-omental splenic autotransplantation is the only method described so far to preserve spleen function after splenectomy; however, it is associated with some postoperative complications. The present study aimed to compare the effectiveness and feasibility of an omentum rotational flap (ORF) with the spleen auto transplant in the omentum (SAO) for preserving splenic function. Forty male Wistar rats were equally divided into two ORF and SAO groups. White blood cell (WBC), hemoglobin (Hb), platelet, immunoglobulin A, M, and G (IgA, IgM, IgG), and complement levels (C3, C4) were measured before and 4 weeks after the surgery. Technetium-99 m scintigraphy was performed to assess the postoperative splenic function in both groups. There was no significant difference between the groups’ preoperative hematological factors. The Hb, C3, C4, IgM, and IgA levels were significantly decreased after intervention in both groups (p < 0.05), and the WBC and platelet counts were significantly reduced after surgery in ORF and SAO groups, respectively. The postoperative level of WBC was significantly lower in ORF compared to the SAO group (p < 0.001). The radioisotope uptake was decreased after surgery in both groups (p < 0.05), and no significant difference was observed in terms of improving radioisotope uptake between the groups (p = 0.63). The duration of surgery was significantly higher in the SAO compared to the ORF group (p < 0.001). In splenic injuries, the omentum rotational flap technique instead of spleen auto transplant in the omentum seems to be an effective surgical method for preserving the function of the spleen, but the evaluation of its safety needs more clinical study.

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Data Availability

The data that support the findings of this study are available from the corresponding author, ME, upon reasonable request.

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Acknowledgements

We would also like to show our gratitude to the Dr Mehrvarz for sharing their pearls of wisdom with us during the course of this research.

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Authors and Affiliations

  1. Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

    Hadi Khoshmohabat & Mohammad Eslamian

  2. Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

    Mohammad Eslamian

Authors
  1. Hadi Khoshmohabat
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Contributions

HKH and ME designed the study, collected and analyzed the data, and wrote the article. The manuscript is an original work of the authors. All data, tables, figures, etc. used in the manuscript are prepared originally by authors. The manuscript has been read and approved by all the authors.

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Correspondence to Mohammad Eslamian.

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Ethical approval

This animal experimental study was approved by the committee of animal research of Baqiyatallah university of medical sciences, Tehran, Iran (Registration number: IR.BMSU.REC.1398.362).

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Khoshmohabat, H., Eslamian, M. Omentum Rotational Flap for Spleen Autotransplantation in Splenic Trauma — Experimental Study. Indian J Surg 86, 184–190 (2024). https://doi.org/10.1007/s12262-023-03800-5

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  • DOI: https://doi.org/10.1007/s12262-023-03800-5

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