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Evaluation of Swallowing Related Quality of Life and Health Related Quality of Life in Patients with Primary Hyperparathyroidism

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Abstract

Primary hyperparathyroidism is a result of overproduction of parathyroid hormone by parathyroid adenoma. Surgical indication of primary hyperparathyroidism is well defined; however, nonspecific symptoms and their effect on quality of patients’ life are not considered on surgical decision-making. The aim of this study is to evaluate the effect of surgical therapy for primary hyperparathyroidism on general and swallowing related quality of life.

This cohort study was conducted prospectively between November 2018 and July 2020.

There were 145 patients with primary hyperparathyroidism included in data analysis. Patient operated for primary hyperparathyroidism were included in the study. General health–related and swallowing-related quality of life was evaluated before and after the surgery.

Improvement of general health–related quality of life was detected in 7 out of 8 domains of short form 36 questionnaire. Improvement of eating-related quality of life was detected in all domains of swallowing-related quality of life questionnaire.

Nonspecific or neuropsychiatric symptoms of PHPT should be evaluated before decision-making for the treatment and should be considered in surgical indications for PHPT.

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References

  1. Perrier ND (2005) Asymptomatic hyperparathyroidism: a medical misnomer? Surg 137(2):127

    Article  Google Scholar 

  2. Trombetti A, Christ ER, Henzen C (2016) Clinical presentation and management of patients with primary hyperparathyroidism of the Swiss Primary Hyperparathyroidism Cohort: a focus on neuro-behavioral and cognitive symptoms. J Endocrinol Invest 39(5):567

    Article  CAS  Google Scholar 

  3. Lundgren E, Szabo E, Ljunghall S (1998) Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidism. BMJ 317(7162):848

    Article  CAS  Google Scholar 

  4. Abboud B, Daher R, Boujaoude J (2011) Digestive manifestations of parathyroid disorders. World J Gastroenterol 17(36):4063–4066

    Article  Google Scholar 

  5. Shah VN, Bhadada SK, Bhansali A (2014) Effect of gender, biochemical parameters & parathyroid surgery on gastrointestinal manifestations of symptomatic primary hyperparathyroidism. Indian J Med Res 139(2):279–284

    PubMed  PubMed Central  Google Scholar 

  6. Bilezikian JP, Brandi ML, Eastell R (2014) Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. J Clin Endocrinol Metab 99:3561–3569

    Article  CAS  Google Scholar 

  7. Koçyiğit H, Aydemir Ö, Ölmez N, Memiş A (1999) Kısa Form-36 (KF-36)’nın Türkçe Versiyonunun Güvenilirliği ve Geçerliliği. İlaç ve Tedavi Dergisi 12:102–106

    Google Scholar 

  8. Demir N, Arslan SS, İnal Ö, Ünlüer NÖ, Karaduman AA (2016) Reliability and validity of the Turkish Version of the Swallow Quality of Life Questionnaire. Turk J Physither Rehabil 27:19–24

    Google Scholar 

  9. Sheldon DG, Lee FT, Neil NJ, Ryan JA Jr (2002) Surgical treatment of hyperparathyroidism improves health-related quality of life. Arch Surg 137:1022–1026

    Article  Google Scholar 

  10. Adler JT, Sippel RS, Schaefer S, Chen H (2008) Preserving function and quality of life after thyroid and parathyroid surgery. Lancet Oncol 9:1069–1075

    Article  Google Scholar 

  11. Tzikos G, Chorti A, Evangelos S (2021) Quality of life in patients with asymptomatic primary hyperparathyroidism after parathyroidectomy: a 3-year longitudinal study. Endocrine Practice 27:16–722

    Article  Google Scholar 

  12. Caillard C, Sebag F, Mathonnet M (2017) Prospective evaluation of quality of life (SF-36v2) and nonspecific symptoms before and after cure of primary hyperparathyroidism (1-year follow-up). Surg 141:153–160

    Article  Google Scholar 

  13. Leong KJ, Sam RC, Garnham AV (2010) Health-related quality of life improvement following surgical treatment of primary hyperparathyroidism in a United Kingdom population. Surg 8:5–8

    CAS  Google Scholar 

  14. Pinchot SN, Youngwirth L, Rajamanickam V, Schaefer S, Sippel R, Chen H (2012) Changes in swallowing-related quality of life after parathyroidectomy for hyperparathyroidism: a prospective cohort study. Oncologist 17(10):1271–1276

    Article  Google Scholar 

  15. Bannani S, Christou N, Guérin C (2018) Effect of parathyroidectomy on quality of life and non-specific symptoms in normocalcaemic primary hyperparathyroidism. Br J Surg 105:223–229

    Article  CAS  Google Scholar 

  16. Brito K, Edirimanne S, Eslick GD (2015) The extent of improvement of health-related quality of life as assessed by the SF-36 and Paseika scales after parathyroidectomy in patients with primary hyperparathyroidism – a systematic review and meta-analysis. Int J Surg 13:245–249

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Surgery, Uşak University Medical School, Uşak, Turkey

    Barış Sevinç, Nurullah Damburacı & Ömer Karahan

  2. Department of Surgery, Kahramanmaraş Afşin State Hospital, Kahramanmaraş, Turkey

    Ahmet Atasever

  3. Department of Surgery, İzmir Katip Çelebi University Medical School, İzmir, Turkey

    Mehmet Hacıyanlı

Authors
  1. Barış Sevinç
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  2. Nurullah Damburacı
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  3. Ömer Karahan
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  4. Ahmet Atasever
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  5. Mehmet Hacıyanlı
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Contributions

• Study conception and design: BS, ND, ÖK, MH.

• Acquisition of data: BS, ND, AA.

• Analysis and interpretation of data: BS, MH.

• Drafting of manuscript: BS, MH.

• Critical revision of manuscript: BS, ÖK, MH.

Corresponding author

Correspondence to Barış Sevinç.

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The authors declare no competing interests.

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This study was registered to clinicaltrials.gov with id: NCT03968510.

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Sevinç, B., Damburacı, N., Karahan, Ö. et al. Evaluation of Swallowing Related Quality of Life and Health Related Quality of Life in Patients with Primary Hyperparathyroidism. Indian J Surg (2022). https://doi.org/10.1007/s12262-022-03549-3

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  • DOI: https://doi.org/10.1007/s12262-022-03549-3

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