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Comparison of MRI Features of Invasive Pleomorphic and Classical Lobular Carcinoma: Differentiation Is Possible?

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Abstract

To evaluate breast MRI and DWI and demographic features of pleomorphic invasive lobular carcinoma (pILC) and classic invasive lobular carcinoma (cILC). Invasive lobular (ILC) is the second most common breast malignancy after invasive ductal carcinoma (IDC) and constitutes the 8–14% of all invasive breast cancers. ILC morphologically can be classified into the classic, alveolar, solid, tubulolobular, and pleomorphic subtypes according to WHO. This study was performed retrospectively. The MRI and demographic features of 18 patients with 23 pILC were compared with those 22 consecutive patients with 27 cILC. There was no significant difference in demographic features of patients, MR appearance, kinetics, and ADC values between two groups. pILC, an aggressive subtype of ILC, cannot be differentiated from cILC with breast MRI.

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Authors and Affiliations

  1. Department of Radiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

    Temel Fatih Yilmaz, Hafize Otcu, Lutfullah Sari, Mehmet Ali Gultekin, Fatma Celik Yabul, Huseyin Toprak & Seyma Yildiz

  2. Department of Pathology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

    Zuhal Gucin

Authors
  1. Temel Fatih Yilmaz
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  2. Hafize Otcu
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  3. Lutfullah Sari
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  4. Zuhal Gucin
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  5. Mehmet Ali Gultekin
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  6. Fatma Celik Yabul
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  8. Seyma Yildiz
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Corresponding author

Correspondence to Lutfullah Sari.

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All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Yilmaz, T.F., Otcu, H., Sari, L. et al. Comparison of MRI Features of Invasive Pleomorphic and Classical Lobular Carcinoma: Differentiation Is Possible?. Indian J Surg 84 (Suppl 3), 722–727 (2022). https://doi.org/10.1007/s12262-021-03228-9

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  • DOI: https://doi.org/10.1007/s12262-021-03228-9

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